List of Articles موش نر

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  1 - Biochemical Effects of Fructose Diet on Obesity in Adult Male NMRI Mice
  Zahra Poyamanesh Parichehr yaghmaei Azadeh Ebrahim Habibi Mahsa Mohammad Amoli
  Introduction: excessive use of artificial sweeteners along with increased body mass raises the risk of cardiovascular diseases, asthma, arthritis, type2 diabetes, stroke, high blood pressure and other diseases and leaves adverse metabolic effects. This study investigate More

  Introduction: excessive use of artificial sweeteners along with increased body mass raises the risk of cardiovascular diseases, asthma, arthritis, type2 diabetes, stroke, high blood pressure and other diseases and leaves adverse metabolic effects. This study investigates the effect of fructose on obesity and its effects on biochemical parameters in adult male mice (NMRI). Materials and Methods: Investigation was carried out in two stages. In the first stage of the treatment which lasted 8 weeks (n=6) the control group received water and rodent food, the obese group had a high-fat diet and the experimental group1received high-fat diet (1382 Kcal) along with 20% of fructose gavage.In the second stage of the treatment which lasted 12weeks, the control group 2, obese group 2 (received rodent food for the last four weeks) and experimental group 2 (received fructose with the same dosage for the last4 weeks) and the study continued for 12 week. The weights were measured every week and the amount of serum fructose and biochemical parameters were measured by sandwich Elisa method. Results: Obese and the experimental group1showed more weight gain as compared to the control 1 and statistically the results were significant (P≤0.001) but experimental 1 showed less weight as compared to the obese 1 but was not significant. Also the experimental group 2 showed higher weight gain as compared to control 2 which was statistically significant (P≤0.001). Fructose levels were higher in all the groups as compared to the control group. The same result was observed for glucose, total cholesterol, TG, LDL with the decrease of HDL. Conclusion: The extra calorie intake is stored in the form of fat leading to weight gain and it is indicated that the receiving of 20% fructose does not play a strong role in gaining weight. Manuscript profile
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  2 - اثر میدان های الکترومغناطیسی با فرکانس 50 هرتز روی غدد تناسلی و هورمون های جنسی موش نر نژاد NMRI
  نفیسه پذیره وحیده سادات عباس نیا کیوان کرامتی بهمن دلالت داوود دورانیان
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  3 - Investigation of the Native Iranian probiotic effect on dermatophytosis consequent ‘Microsprum canis in male Wistar rats in vitro
  nayerh akbary fazeli
  Probiotics are live organisms applying advantageous effects to their host, and are often taken as supplementary food or complementary medicine. Nowadays, the rate of probiotic products is widely increased among the world. Reinforcement of body immunity, decrease of seru More

  Probiotics are live organisms applying advantageous effects to their host, and are often taken as supplementary food or complementary medicine. Nowadays, the rate of probiotic products is widely increased among the world. Reinforcement of body immunity, decrease of serum cholesterol and digestive infection, less risk of cancer attack and decrease of skin allergies and e.t.c., all are the practical features of probiotics. The dermal fungal diseases are infections caused by various dermatophyt spieses attacks to the human and animal skin epiderm, aiming at the skin creatine tissues and make infections with intense or mild clinical significances.During this study, the accordance probiotic was chosen in a laboratory condition, and then 40 wistar male mice, same in age and weight, in a standard condition were divided randomly to five control groups; including positive and negative and three split tests. The process of treatment in three different feeding conditions was examined immediately after applying food contamination and ointment and reaching the maximum level of contamination. The results extracted from the research proved the positive effect of probiotics on the fungus named ‘Microsprum canis’ and the treatment of consequent disease. Manuscript profile
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  4 - Effect of phytosterol and Bacillus coagulant probiotic in reducing blood cholesterol
  Maryam Arjomandi far Bahareh Pakpour Rahebeh Amiri Dehkharghani
  Target and background: In recent years, many studies have been conducted on high-risk factors for some blood lipids, which can lead to the development of cardiovascular diseases. The most important goal of this study is to investigate the effect of phytosterol and Bacil More

  Target and background: In recent years, many studies have been conducted on high-risk factors for some blood lipids, which can lead to the development of cardiovascular diseases. The most important goal of this study is to investigate the effect of phytosterol and Bacillus coagulant probiotic on the reduction of blood cholesterol in adult rats. Material and Methods: 40 Male NMRI mice with a weight of 25-30g were used .The mouse were divided into 5 groups of 8, including: control group, HCD group (1% of the weight of the food consumed cholesterol diet), Experimental group 1 (daily, in addition to cholesterol diet, 0.1g of phytosterol Experimental group 2 (daily, in addition to cholesterol diet, 0.2g of Bacillus coagulant bacteria plus animal oil was gavaged), Experimental group 3 (daily, in addition to cholesterol diet, 0.1g combination of phytosterol and Bacillus coagulants probiotic were digested with germicidal oil). Sperry samples were taken from the blood samples at the end of the experiments, and cholesterol, triglycerides, HDL and LDL blood samples were measured and. Results: Cholesterol, triglyceride, HDL and LDL showed a significant decrease compared to the control group. Conclusion: According to the above results, it can be said that phytosterol and Bacillus coagulant probiotic simultaneously decrease blood lipids, and therefore, it is recommended to use this pump.     Manuscript profile
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  5 - The Effect of Movento Insecticide on the Fertility Rate in Male Balb/c Mice
  Ghodrat Ebadi Manas
  10.22034/ascij.2023.1991328.1511
  Today, due to the indiscriminate use of poisons and the resistance of pests to them, new types of poisons are produced every year. Movento is the latest insecticide that is used in pistachio orchards to control the psyllid pest, whose side effects on the reproductive sy More

  Today, due to the indiscriminate use of poisons and the resistance of pests to them, new types of poisons are produced every year. Movento is the latest insecticide that is used in pistachio orchards to control the psyllid pest, whose side effects on the reproductive system have not been investigated. The aim of this study was to investigate the effect of Movento on fertility in Balb/c mice. In this study, 18 adult and healthy male Balb/c mice were prepared and kept under standard conditions. Each group consisted of 9 mice. Mice were randomly divided into experimental and control groups. The experimental group received 79 mg/kg Movento and the control group received the same amount of distilled water daily for 60 days through oral gavage. At the end of the study, the mice were euthanized by injecting a mixture of xylazine and ketamine. Epididymal tail of the testes of mice was separated and placed in HTF culture medium. The parameters of sperm count, sperm viability, DNA damage of sperm, immature sperms and fertilization ability of sperms and blastocyst were evaluated. The data obtained from the study were analyzed by ANOVA method. The findings showed that sperm viability, the percentage of fertilized oocytes, two-celled and four-celled embryos, and the number of blastocysts were significantly reduced in the experimental group compared to the control. Also, sperms count in the experimental group compared to the control group decreased but was not significant. However, immature sperms and DNA damage of sperm in the experimental group was increased compared to the control group. Therefore, it can be concluded that Movento poison reduces fertility in mice by DNA damage of sperm and chromatin. Manuscript profile