List of Articles زیست‌سازگار

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  1 - Green Synthesis of Silver Nanoparticles by Cinnamon Extract and Evaluation of Their Photocatalytic Properties under Visible Light for Degradation of Methyl Orange Dye
  R. Shekari-Moghaddam M. Mohammadi S.H. Hekmatara A. Darehkordi P. Salarizadeh
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  2 - Preparation of Biocompatible Polyvinyl Alcohol Composite Nanofibers Containing Artemisia aucheri Extract with Desirable Antibacterial Properties
  V. Nezamabadi M.R. Akhgar B. Tahamipour P. Rajaei
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  3 - Synthesis and Biocompatibility of Mg-CaP Nanoparticles
  A. Adibfar A. Behnamghader
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  4 - One-step Electrodeposition of Graphene–Chitosan Biocompatible Nanocomposite Coating onto Stainless Steel
  H. Hassannejad A. Nouri
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  5 - Synthesis, Characterization and Morphological Investigation of FAp-TiO2 Nanocomposite Coatings Used in Ti-based Dental Implants
  N. Sasani J. Vahdati Khaki S.M. Zebarjad H. Khadivi Ayask
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  6 - Synthesis and characterization of magnesium-based metal-organic frameworks and investigating the effect of coordination solvent on their biocompatibility
  Saeed Reza Hormozi Jangi
  In this contribution, magnesium-based metal-organic frameworks (average size, 430 nm) were synthesized by a simple, low-cost, and high-efficient method utilizing different coordination solvents. The as-synthesized frameworks were then characterized by several characteri More

  In this contribution, magnesium-based metal-organic frameworks (average size, 430 nm) were synthesized by a simple, low-cost, and high-efficient method utilizing different coordination solvents. The as-synthesized frameworks were then characterized by several characterization methods. The formation of metal-organic framework(MOF( coordination bindings was confirmed by FT-IR, EDX, UV-Vis, and SEM analyses. The organic content of the as-prepared MOFs was quantified by elemental analysis. The results showed that the coordination yield in protic solvents is higher than that of the aprotic solvents. In contrast, the organic content of the MOFs prepared in aprotic media was found to be more than that of the protic solvent due to the competitive role of aprotic solvents in the coordination process. The effect of coordination solvent on the biocompatibility of as-synthesized MOFs was also investigated using the standard protein absorption-desorption and hemolysis analysis. The protein adsorption results showed that the as-synthesized MOFs with protic solvents absorbed about 0.02 μg μg-1, which is 17.5-fold lower than that of the aprotic solvents. The hemolysis ratio of the synthesized sample in protic solvent was calculated at about 0.3%, which is 5 times lower than the hemolysis ratio of the synthetic sample in aprotic media, indicating their high erythrocyte compatibility. These findings reveal that the biocompatibility of magnesium-based metal-organic frameworks is significantly affected by the coordination solvent. The Authors strongly recommend using the results of this contribution for the synthesis of biocompatible carriers for drug and enzyme immobilization aims. Manuscript profile
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  7 - The role of metal and non-metal nano oxides in improving the physical properties of drugsin drug formulation
  Somaye Golsanamlou Aliakbar Tarlani
  10.30495/jacr.2023.1984362.2116
  In this review article, the role of porous inorganic oxide compounds as drug carriers in order to improve the physical properties of drugs is discussed. Solubility and permeability of drugs in the digestive system is one of the determining factors of oral bioavailabilit More

  In this review article, the role of porous inorganic oxide compounds as drug carriers in order to improve the physical properties of drugs is discussed. Solubility and permeability of drugs in the digestive system is one of the determining factors of oral bioavailability of drugs. There have always been drugs whose solubility needed to be optimized to prepare a suitable oral formula. Today, as a result of extensive research and the emergence of new drugs, the number of drugs that have solubility problems has increased, including some cardiac drugs that are in the second class of drugs and have low solubility. The low solubility of these types of drugs has caused therapeutic limitations because to increase the effectiveness of these drugs, a higher dose of them has to be prescribed which causes the drug to accumulate in the blood and deposit in the blood vessel wall. Therefore, drugs need a drug carrier to improve their performance. Drug delivery systems (DDS) including biodegradable polymer nanoparticles, polymer micelles, solid nanoparticles, nanoliposomes, dendrimers, magnetic nanoparticles and quantum dots have been used for this purpose for decades. However, in recent years, the use of metal and non-metal oxides in modern drug delivery systems has attracted the attention of scientists. Compared to other conventional compounds, these inorganic porous compounds have many advantages, including improving solubility and stability, the possibility of controlling the drug dosage, controlling the kinetics of drug release, delivering the drug to the target tissue, reducing side effects, increasing the biocompatibility of the drug, etc. Therefore, the use of new drug delivery systems based on the new generation of metal and non-metal oxides in order to improve the solubility, permeability and biocompatibility of drugs is an important and essential step in the formulation of drugs, which has been discussed in this article. Manuscript profile
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  8 - Fabrication and Evaluation of Morphological, Structural and Biocompatibility Properties of Chitosan Nanofibrous Scaffolds Coated with ZIF-8 Metal-organic Framework for Application in Wound Dressing
  Mahdi Hasanzadeh
  In this study, chitosan-based nanofibrous scaffold was produced for application in wound dressing by electrospinning method. Then, the zinc-based metal-organic framework (ZIF-8) was in situ synthesized method on nanofibrous scaffold. The effect of growth time of ZIF-8 c More

  In this study, chitosan-based nanofibrous scaffold was produced for application in wound dressing by electrospinning method. Then, the zinc-based metal-organic framework (ZIF-8) was in situ synthesized method on nanofibrous scaffold. The effect of growth time of ZIF-8 crystals on chitosan nanofibrous scaffolds was studied in order to achieve a uniform and continuous coating. The morphology and structure of the produced scaffolds were evaluated using scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). In order to evaluate the potential of fabricated scaffolds in wound dressing, surface wettability, antibacterial activity, biocompatibility and cell viability were also investigated. The electron microscope images showed that after 30 minutes, ZIF-8 nanoparticles grew with a relatively uniform distribution with an average size of 80 nm on the chitosan scaffold. The results showed that the scaffolds were biocompatible after 24 hours of cell culture and also had antibacterial properties against Gram-negative and Gram-positive Escherichia coli and Staphylococcus aureus, respectively. Due to the appropriate structural and morphological properties as well as the appropriate biocompatibility and antibacterial performance of the nanofibrous scaffold coated with a metal-organic framework, it can be used as a suitable candidate in wound dressing applications. Manuscript profile