Leptin, after passing from sertoli-cells and entering into the balls, can cause the prevention of releasing testosterone and can control releasing glycoproteins though a paracrine network and also defect or resistance of Leptin causes extreme deficiency in the function More
Leptin, after passing from sertoli-cells and entering into the balls, can cause the prevention of releasing testosterone and can control releasing glycoproteins though a paracrine network and also defect or resistance of Leptin causes extreme deficiency in the function of genitourinary system in human and animal models. As Leptin do its own physiological functions with the reaction to Leptin receptor and also leap in coding gene of Leptin receptor causes reduction in density of testosterone serum, normal sexual minority and sterility. On the other hand, any researches haven’t been conducted clearly on relationship of testosterone and Leptin in fertile and sterile men, this research has been performed, about this subject. Elisa is one of the best laboratorial and research methods all over the world and used in identifying the small amounts of vital hormones and molecules in clinical medicine and research tests. In this research, the effect of Leptin on testosterone in serum of fertile and sterile men has been researched and compared.The result is that the amount of the testosterone in sterile persons is more than fertile persons but the amount of Leptin in fertile persons is more than sterile persons. Therefore, determining the treatment strategy to cure the sterile men is the usage of effective medicines and diet with Leptin.
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Cadmium is dangerous due to the properties such as persistence and accumulation in the environment. The aim of this study is of the protective effect of chieko fruiton the damage of testes tissue in rats treated with cadmium. This experimental study was performed More
Cadmium is dangerous due to the properties such as persistence and accumulation in the environment. The aim of this study is of the protective effect of chieko fruiton the damage of testes tissue in rats treated with cadmium. This experimental study was performed on 42 adult maleWistar rats. The rats were divided in to 7 groups. The control group received food and water. Sham1 group wereinjected with 0.2 ml distilled water. Sham2 group was injected with 0.2 mg/Kg B.W.Cadmium. Sham3 group wereinjected with 100 mg/Kg B.W. chieko extract. The experimentalgroups1, 2 and 3 in the first day of testing, 0.2 mg / Kg B.W. Also cadmium(0.2 mg/Kg B.W.) and50, 100 and 200mg / Kg B.W. chieko extractwas injected to the experimental 1, 2 and 3 groupsrespectively. After 14 days, the mice hearts were bled and the serumlevelsof their sex hormone were examined.Data was collected by using SPSS software and by one-way variance analytical tests (ANOVA) in significance P
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On a 7-years-old dog with Azoospermia three conventional drugs in breeding techniques were tested to assess the
effects and reproductive improvement of them. the Drugs that chosen include gonadotropin (GnRH) in commercial
name Cystorelin، 50 micrograms subcutaneously More
On a 7-years-old dog with Azoospermia three conventional drugs in breeding techniques were tested to assess the
effects and reproductive improvement of them. the Drugs that chosen include gonadotropin (GnRH) in commercial
name Cystorelin، 50 micrograms subcutaneously 60 minutes prior to sperm collection , prostaglandin (PGF2α)
in commercial name Veteglan , 0/005 mg/kg subcutaneously 15 minutes prior to sperm collection and Oxytocin
10IU per dog intramuscularly 10 minutes prior to sperm collection. Semen collected from this animal by manual
semen collection technique and we had 7 days sexual rest between each collection. during the semen collection the
dog’s libido was assessed and then semen Volume , Semen PH , semen color , semen concentration per ml ,total
count of spermatozoa , progressive motility forward percent , morphologically normal spermatozoa percent and
Total normal motile spermatozoa (TMNS) was evaluated. The samples did not show any traces of semen quality
change when dog received prostaglandin and oxytocin and there is no spermatozoa in that samples. But when the
sampled animal was under the influence of gonadotropin therapy semen quality improved dramatically in addition
we have one billion and twenty-four millions of spermatozoa as the total count of the sample. Two hypotheses are
proposed for this quality improvement. The frst one say the prescribing of gonadotropin in this dog, increased the
animal blood testosterone index and stimulate the seminiferous ducts to released spermatozoa. The second one
say because of the clinical condition of the animal it seems to had IHH syndrome and during the administration of
gonadotropin the body hormonal system was regulated and released the sperm cells. Finally, it can be concluding
that the use of gonadotropins may be improving the quality of semen of animals that have Azoospermia with
source of hormonal abnormality.
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