List of Articles بیضه موش

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  1 - media conditioning on the antioxidant and histomorphometry of testis following caffeine consumption in adult male rat
  Davoud Rahimi Jabbar Bashiri Alireza NoorAzar رقیه Pouzesh Jadidi Daryoush Mohajeri
  10.30495/jvcp.2023.1981208.1398
  Considering the consumption of caffeine as a supplement favored by theathletes and the proof of its long-term abuse effects on male fertility, the purpose of this study was to investigate the effect of moderate aerobic training combined with the conditioning of Sertoli More

  Considering the consumption of caffeine as a supplement favored by theathletes and the proof of its long-term abuse effects on male fertility, the purpose of this study was to investigate the effect of moderate aerobic training combined with the conditioning of Sertoli cell media in testicular damage caused by caffeine consumption.For this purpose,30male Wistar rats were tested in5groups.For4weeks, the groups received caffeine at a dose of200 mg/kg orally and group1received of distilled water.42days after that, the conditioned media of Sertoli cells was injected into the efferent ducts of the rats in the treatment group.After8 weeks, mice were sampled.Tissue samples were studied by histomorphometry andSOD,,GPX, TACand MDA.The group under the influence of caffeine compared to the healthy group, significantly(p<0.01).had lower values of seminiferous tubule diameter, epithelium height, interstitial thickness,TAC, SODandGPXand higher values ofMDA. Respectively, the three groups affected by caffeine along with exercise treatment, treatment with media conditioning and exercise along with media conditioning compared to the group affected with caffeine, have higher values of seminiferous tubule diameter, epithelium height, interstitial thickness,TAC, SODandGPX,and MDA values were lower.In the treatment group with media conditioning and exercise, there was a significant difference in the amount of decrease and increase in the mentioned parameters compared to the other two treatment groups (p<0.05).The results of the present study showed that the use of Sertoli cell media conditioning and aerobic exercise at the same time, with synergistic effects, improves the antioxidant defense indices and reduces the harmful effects of caffeine in the testicular tissue of rats.. Manuscript profile
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  2 - Study of the effect of pioglitazone on testicular function after scrotal heat induced shock in the rat
  سعید Mohammad Hoseini مهرداد Neshat Gharamaleki سیداسماعیل Safavi
     Testicular heat shock even for a single short period can induce destruction in testicular tissue and disturbances spermatogenesis. Pioglitazone is an anti-inflammatory and anti-oxidative drug which is used widely in diabetic patients. The main aim of this s More

     Testicular heat shock even for a single short period can induce destruction in testicular tissue and disturbances spermatogenesis. Pioglitazone is an anti-inflammatory and anti-oxidative drug which is used widely in diabetic patients. The main aim of this study is evaluation of effect of pioglitazone on testicular tissue after scrotal heat shock. For this purpose, 54 male Wistar rats were randomly divided in to 9 of 6 rats. In the first three groups which were used as control, the scrotum of animals were submerged in 230c water. In the other three groups (treatment 1), the scrotum was submerged in 430c water for 15 minutes and then the animals received normal saline for 15, 30 and 60 days. In the final three groups (treatment 2) after scrotal heat shock induction, pioglitazone was injected at a dose of 20 mg/kg for 15, 30 and 60 days. At the end of the experimental periods, testicular tissue samples were obtained for pathological and histomorphometerical studies. The results were analyzed with one-way ANOVA and Tukey test and p Manuscript profile