List of Articles آسیب شناسی بافتی

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  1 - Study of histopathology and bioaccumulation of Iron oxide (Fe2O3) nanoparticles in liver of common carp (Cyprinus carpio)
  Omidzahir, Sh.*, Khodabandehloo, R. , Kardel, F. , Elmi, F. .
  Increasing production of nanoparticles and its usage in different industries has led concerns about its dangers and toxicity in the environment, but there is not enough information about their toxicity effects, and their safety is unknown. This study tried to evaluate t More

  Increasing production of nanoparticles and its usage in different industries has led concerns about its dangers and toxicity in the environment, but there is not enough information about their toxicity effects, and their safety is unknown. This study tried to evaluate the bioaccumulation and histopathology of iron oxide nanoparticles (Fe2O3) in liver tissues of Common carp (Cyprinus carpio). To this aim, Common carp fishes were prepared from a fish farm and transferred to the laboratory. After adapting to the laboratory conditions for a week, the fishes were divided into 4 treatments. The first treatment was considered as control and the other treatments received 50, 75 and the 100 milligrams per liter of iron oxide nanoparticles. In the days 14, 21 and 28, the fishes were randomly selected from each treatment and the liver tissues were separated and were examined for bioaccumulation and histopathology. In the present study the result of the statistical analysis showed in the day 21 of the experiment, the concentration of Iron was significantly higher than other treatments in the liver.  Histopathological examination in liver showed the most lesions in treatment 4 in day28 included severe necrosis and vacuolar degeneration, infiltration of inflammatory cells mild and hyperemia. The results of present study showed by increasing of dose and exposure time of iron oxide nanoparticles (Fe2O3) the lesions in hepatocytes increased and iron concentration in liver decreased. Manuscript profile
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  2 - Study on Gill Tissue Lesions in Kutum (Rutiluskutum) Fry During Exposure to Heavy Metals, Iron and Zinc
  Nikta Mehdipour syeid Ali Akbar Hedayati MohammadReza Imanpour
  Inroduction & ObjectiveThis studyaimed to investigate the effects of heavy metals such as iron and zinc on the gills of fish Rutiluskutum.Inthis regardMaterials and Methods:120kutum were prepared with laboratory conditions testing in 30 days at concentrations of FeCl2 1 More

  Inroduction & ObjectiveThis studyaimed to investigate the effects of heavy metals such as iron and zinc on the gills of fish Rutiluskutum.Inthis regardMaterials and Methods:120kutum were prepared with laboratory conditions testing in 30 days at concentrations of FeCl2 19.5 mg/L and ZnCl2 3.9 mg/L.Tissue samples were caught at three periods of 7, 15 and 30 days.ResultsThe results indicate that with the progresses of exposure time for iron, damage to gill tissue were more severed such as hypere mia and hemorrhage, fractures and connectivity of secondary lamella and secondary lamella shortening, bladegill, lamella of swollen multi-cellular. So in 30 days , the maximum deta chmentw as seen in primary and secondary lamella. Conclusion: The amount of gill tissue damage of various concentrations metals were as follows: Fe>Zn respectively and in zinc treatment was increased. Manuscript profile
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  3 - Histopathological study of osteoporotic changes after experimental creation of osteoporosis by ovariectomy in the rat
  داریوش Mohajeri مهران Mesgari Ali Rezaie Amin Balila
  In order to study the histopathology of osteoporosis during menopause, 80 female Sprague-Dawley rats with approximate age of 10 weeks were allocated to 10 groups of 8 rats each (C1, C2 and C3 as control, S1, S2 and S3 as sham, T1, T2 and T3 as treatment groups and C0 as More

  In order to study the histopathology of osteoporosis during menopause, 80 female Sprague-Dawley rats with approximate age of 10 weeks were allocated to 10 groups of 8 rats each (C1, C2 and C3 as control, S1, S2 and S3 as sham, T1, T2 and T3 as treatment groups and C0 as one pure control group). The nutritional and maintenance conditions were similar in all groups. Treatment groups (T1, T2 and T3) were bilaterally ovariectomized using right and left flank approach. Sham groups (S1, S2 and S3) underwent operation in which ovaries were exposed from the same approach but left intact. Treatment (T1, T2 and T3) and their related control groups (C1, C2 and C3) were euthanized at 5, 12 and 21 weeks respectively after ovariectomy. After necropsy, both tibia and femur bones were totally removed and fixed in 10%  buffered formalin, decalcified and tissue specimens stained with H&E for histopathological study. Microscopically, osteoporosis was prominent in treatment groups T2 and T3 although it was more severe in treatment group T3. Statistically, differences between ovariectomized groups (T1, T2 and T3) regarding the severity of osteoporosis with 99% confidence were significant (P<0.01). Significant differences between treatment group T1 and control groups were not observed (P>0.05). Manuscript profile
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  4 - بررسی آسیب شناسی بافتی درمسمومیت تجربی با دیازینون در بچه ماهیان قزل آلای رنگین کمان(Oncorhynchus mykiss)
  مسعود سعیدی فر حبیب وهاب زاده رودسری عباسعلی زمینی الهام میررسولی رضوان اله کاظمی
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