List of Articles : tramadol

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  1 - Effect of oral tramadol on rat Spleen tissue in male Wistar rats
  sahar molzemi mohsen aminian Mohammad Afshar Ardalan Amir Hossein Ashnaei
  10.30495/jdb.2021.682710
  Introduction : Tramadol the right drugs are synthetic opioid analgesics or Epoxied. The aim of this study was to evaluate the effect of oral tramadol on Spleen in rats Wistar male rats.Methods: In this study, 60 male Wistar rats randomized into 3 groups (1 control group More

  Introduction : Tramadol the right drugs are synthetic opioid analgesics or Epoxied. The aim of this study was to evaluate the effect of oral tramadol on Spleen in rats Wistar male rats.Methods: In this study, 60 male Wistar rats randomized into 3 groups (1 control group, and experimental groups of 1, 2). In control group adequate serum physiology and in experimental groups a dose of mercuric chloride infused into peritoneal cavity, for 30 days. The amount of gavage tramadol were, 50ml /kg group 2, 100 ml /kg , every other day for 30 days. After the end of the day appointed for Histological analysis Some blood parameters of Spleen samples, were tested.Results :And & two experimental groups a very high density and exposure area is full of blood and lymphoid cells. Particles of hemosiderin in both groups showed a significant increase..Conclusion: This study showed that long-term oral administration of Tramadol causes histological changes in the SpleenKeywords: tramadol, Spleen, mouse, rats, Wistar Manuscript profile