Development of liposomal formulations carrying antibiotics
Subject Areas : biotechnology
1 - Department of Biology, Biological Science College, Varamin-Pishva Branch, Islamic Azad University, Varamin-Pishva, Iran
Keywords: drug carriers, liposome, antibiotic, resistant microorganisms,
Abstract :
Since the advent of antibiotics, selective pressure on microorganisms has caused the formation of resistant types. Different generations of antibiotics have been designed and used to fight pathogens, but at the same time, more resistant types of pathogens have been spread, so it is necessary to use new strategies to deal with infectious agents. The development of nanoscience in the field of medicine was a suitable solution for this purpose, and pharmaceutical nanocarriers were developed. Liposomes are nanocarriers with a lipid body whose features such as biocompatibility, bioavailability, targeted transfer, amphiphilic properties, integration with membranes, slow and controlled drug release have attracted the attention of researchers. In this review article, an attempt has been made to provide information about the benefits of this drug system by studying scientific documents in the field of antibiotic-carrying liposomes.