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        1 - The Effect of Dried Barberry Root Supplementation on Muscular Pain and Serum Antioxidant Enzymes Following a Session of Eccentric Exhaustion Exercise in Non-athlete Women
        Nematollah Nikmanesh hadi ghaedi
        Introduction: Antioxidant use can affect delayed muscle soreness, inflammation, and oxidative markers. The aim of the present study was to investigate the effect of dried barberry root supplementation on muscle pain and serum superoxide dismutase (SOD), catalase (CAT) a More
        Introduction: Antioxidant use can affect delayed muscle soreness, inflammation, and oxidative markers. The aim of the present study was to investigate the effect of dried barberry root supplementation on muscle pain and serum superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) following a session of eccentric exhausting activity in non-athlete women. Materials and methods: In this quasi-experimental study, thirty non-athlete women aged 20 to 30 years were randomly divided into three groups of 10, including 1- eccentric exhaustion activity (control group), 2- eccentric exhaustion activity + placebo (placebo group) and 3- eccentric exhaustion activity + barberry supplement (Barberry group). On the pretest day, all three groups participated in an exhaustive eccentric activity. Blood samples were taken from the subjects before and after the activity. Then, the subjects participated in a group-specific supplementation program for 2 weeks. Groups 2 and 3 received dried barberry root and flour powder with a daily dose of 3 capsules of 250 mg respectively. After two weeks of receiving the interventions, all three groups again participated in the post-test similar to the pre-test in the eccentric exhausting physical activity with the same intensity and duration .Blood samples were taken again from the subjects before and after this activity To analyze the data, 2×  4 factor analysis of variance (2 groups and 4 times of measurement)  including Bonferroni post- hoc test was used(P≥0.05). Findings: Eccentric exhausting activity and eccentric exhausting activity+barberry supplement had no significant effect on changes in serum levels of SOD and CAT (P≤0.05). Althougheccentric exhausting activity significantly increased serum GPX levels and muscle pain (P≤0.05); this increase was less in the barberry supplement group (P≥0.05). Conclusion: It seems that one session of eccentric exhausting activity can increase muscle soreness and serum GPX levels in non-athlete women. However, 14 days of barberry supplementation can reduce its levels. Manuscript profile