Chemical constituents, antimicrobial and antioxidant activities of Leptoderris brachyptera (Benth.) Dunn and Leptoderris micrantha Dunn essential oils
Subject Areas : Essential Oils: Classical and Advanced Techniques for Isolation and Biological Activities
Ganiyat Oloyede
1
(Organic Chemistry Unit, Department of Chemistry, University of Ibadan, Nigeria)
Michael Ibok
2
(Organic Chemistry Unit, Department of Chemistry, University of Ibadan, Nigeria)
Thomas Ojo
3
(Organic Chemistry Unit, Department of Chemistry, University of Ibadan, Nigeria)
Keywords: Antimicrobial Activity, Antioxidant effect, Essential oils, <i>Leptoderris micrantha</i> Dunn, <i>Leptoderris brachyptera</i> (Benth.) Dunn, Hydrodistillation,
Abstract :
This study examined the composition of the essential oils long with corresponding antioxidant and antimicrobial properties of the leaves and stems of Leptoderris brachyptera and Leptoderris micrantha. Essential oils were obtained by hydrodistillation method using Clevenger-type apparatus, while identification and characterization were done by gas chromatography-mass spectroscopy (GC-MS) technique. The antimicrobial property was evaluated by the agar diffusion method and antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical method. Essential oils yields range from 0.4%-0.8%. GC-MS analyses revealed twenty-six and five compounds in leaves and stem of Leptoderris brachyptera representing 96.4% and 92.6% of which phytol (11.2%) and 4-(1H-pyrazol-1-yl)benzeneamine (60.8%) as the most abundant components, respectively. Nineteen and thirteen volatile constituents were identified from leaves and stems of Leptoderris micrantha representing 94.3% and 94.1% with phytol (30.7%) and palmitic acid (36.4%), respectively. However, the essential oils exhibited moderate antimicrobial and antioxidant activities.
Adams R.P., 2007. Identification of Essential Oil Components by GC-MS. Allured Publication Corp., Carlo Stream, II. USA.
Addo-fordjour, P., Anning, A.K., Amaniampong, E., Serwaa-Agywei, P., 2008. Diversity and distribution of climbing plants in a semi-deciduous Rain Forest, FNUST Botanic Garden, Ghana. Inter. J. Botan. 2, 186-195.
Balogun, O.S., Ajayi, O.S., Adeleke, A.J., 2017. HexahydrofarnesylAcetone-rich extractives from Hildegardia barteri. J. Herbs, Spices Med. Plants. 1-8. doi: 10.1080/10496475.2017.1350614
Burkill, H.M., 2000. The Useful Plants of West Tropical Africa, Vol 3; 2nd Ed. Kew, UK, Royal Botanical Gardens.
Camila, C.M.P.S., Mirian, S.S., Vanine, G.M., Luciana, M.C., Antonia, A.C.A., Guilherme, A.L.O., Jéssica, P.C., Damião, P.S., Rivelilson, M.F., Reinaldo, N.A., 2013. Antinociceptive and antioxidant activities of phytol in vivo and in vitro models. J. Neurosci. 2013, 1-9.
Chaverri, C., Cicció, J., 2015. Leaf and flower essential oil compositions of Gliricidia sepium (Fabaceae) from Costa Rica. Amer. J. Essen. Oils Nat. Prod. 2(3), 18-23.
Famobuwa, O.E., Oloyede, H.O., Bello, I.J., 2016. Synergistic antioxidant and anti-bacterial activities of Croton zambesicus MülLeptoderris-Arg. (Euphorbiaceae) Leptoderris micrantha Dunn (Fabaceae) and Carpolobia lutea G. Don (Polygalaceae). Int. J. Pharm. Sci. Res. 1(4), 05-08.
Gabon, F.I., 2016. Conservatoire et Jardin botaniques & South African National Biodiversity Institute, 49, 220-225.
Ghannadi, A., Tavakoli, N., Mehri-Ardestani, M., 2003. Volatile constituents of the leaves of Ziziphus spinachristi (L.) Willd. From Bushehr, Iran. J. Essen. Oil Res. 15, 191-192.
Judd, W.S., Campbell, C.S., Kellogg, E.A., Stevens, P.F. and Donoghue, M.J., 2002. Plant systematics: a phylogenetic approach. Sinauer Axxoc. 287-292.
Khallouki, F., Younos, C., Soulimani, R. and Bessière, J., 2002. Chemical composition of the essential oil of Ononis natrix L. Fabaceae. J. Essent. Oil Res. 14. 431-432.
Kumar, P.P., Kumaravel, S., Lalitha, C., 2010. Screening of antioxidant activity, total phenolics and GC-MS study of Vitex negundo. Afr. J. Biochem. Res. 4(7), 191-195.
Magallón, S.A., Sanderson, M.J., 2001. Absolute diversification rates in angiosperm clades. Evolution 55(9), 1762-1780.
Magiatis, P., Melliou, E., Skaltsounis, A.L., 1999. Chemical composition and antibacterial activity of essential oils of Pistacia lentiscus var. chia. Planta Med. 65(8), 749-752.
Martins, A.P., Salgueiro, L.R., Goncalves, M.J., 2000. Antibacterial activity and chemical composition of the bark oil of Croton stelluifer, and endemic species from St. Tome and Principy. Planta Med. 66(7), 647-650.
Mevy, J.P., Bessiere, J.M., Dherbomez, D., Millogo, J., Viano, J., 2007. Chemical composition and some biological activities of the volatile oils of a chemotype of Lippia chevalieri Moldenke. Food Chem. 101(2), 682-685.
Mohadjerani, M., Asadollahi, S., 2019. Veronica crista-galli Steven and Veronica persica Poir. as anticancer and antioxidant plants in-vitro. Trends Phytochem. Res. 3(1), 61-66.
Mohammadhosseini, M., 2017. The ethnobotanical, phytochemical and pharmacological properties and medicinal applications of essential oils and extracts of different Ziziphora species. Ind. Crops Prod. 105, 164-192.
Morais, C.B., Scopel, M., Pedrazza, G.P.R., da Silva, F.K., Dalla Lana, D.F., Tonello, M.L., Miotto, S.T.S., Machado, M.M., De Oliveira, L.S., Fuentefria, A.M., Zuanazzi, J.A., 2017. Anti-dermatophyte activity of Leguminosae plants from Southern Brazil with emphasis on Mimosa pigra (Leguminosae). J. Med. Mycol. 27(4), 530-538.
Nahar, L., Sarker, S.D., 2019. UPLC in phytochemical analysis. Trends Phytochem. Res. 3(1), 1-2.
Nangue, Y.D., Llorent-Martínez, E.J., Fernández-de Córdova, M.L., Ngangoum, D.A.M., Nguelefack, T.B., Azebaze, A.G.B., Dongmo, A.B., 2019. Phytochemical study and anti-inflammatory activity of the roots of Mangifera indica L. in lipopolysaccharide (LPS)-stimulated peritoneal macrophages. Trends Phytochem. Res. 3(1), 53-60.
Neńić, M., Stojanović, N., RanĎelović, P., Radulović N., 2018. Effects of acorenone-type Acorus calamus essential oil on rat gastric fundus contractions and intestinal transit. 49th International Symposium on Essential Oils (ISEO2018). Phys. Chem. Tech. 16(1), 139.
Ogunlana, O.E., Ogunlana, O.O., Farombi, E.O., 2008. Morinda lucida: Antioxidant and reducing activities of crude methanolic stem bark extract. Adv. Nat. Appl. Sci. 2, 49-54.
Olaoluwa, O.O., Aiyelaagbe, O.O., Irwin, D., Reid, M., 2013. Novel anthraquinone derivatives from the aerial parts of Antigonon leptopus Hook & Arn. Tetrahedron 69(33), 6906-6910.
Olaoluwa, O., Moronkola, D., Taiwo, O., Iganboh, P., 2018. Volatile oil composition, antioxidant and antimicrobial properties of Boerhavia erecta L. and Euphorbia hirta L. Trends in Phytochem. Res. 2(3), 171-178.
Oloyede, G.K., Oladosu, I.A., Shodia, A.F., 2010. Chemical composition and cytotoxicity of the essential oils of Crinum ornatum (Ait.) Bury. Afri. J. Pure and App. Chem. 4(3), 035-037.
Oloyede, G.K., Olatinwo, M.B., 2014. Phytochemical investigation, toxicity and antimicrobial screening of essential oil and extracts from leaves and stem bark of Hura crepitans (Euphorbiaceae). Academ. Arena 6(5), 7-15.
Oloyede, G.K., Ojeyinka, B.K., 2019. Effect of solvent on chemical composition and antioxidant activities of Abelmoschus esculentus (L.) Moench Pods oils extracts. J. App. Sci. 19, 133-139.
Onocha, P.A., Oloyede, G.K., Akintola, J.A., 2016. Chemical composition, free radical scavenging and antimicrobial activities of essential oil of Mariscus alternifolius Vahl. Open Conf. Proc. J. 7, 160-167.
Rukangira, E., 2001. Medicinal Plants and Traditional Medicine in Africa: Constraints and Challenges. Sustainable Development International, 4, 179-184.
Sonibare, M.A., Oke, T.A., Soladoye, M.O., 2014. A pharmacobotanical study of two medicinal species of Fabaceae. Asian Pacific J. Tropic. Biomedicin. 4(2), 131-136.
Yhiya, M.A., Amani, M.M, Mona, G.Z., Mohamed, S.A., 2015. The genus Machaerium (Fabaceae): Taxonomy, phytochemistry, traditional uses and biological activities. Nat. Prod. Res. 29(15), 1388-1405.
Youmans, G.P., Peterson, P.Y., Soumers, H.M., 1967. The Biological and Clinical Basis of Infectious Diseases. Longman London, pp. 721-725.