Effect of Essence of Satureja rechingeri on Blood Glucose and Serum Lipids in Diabetic Male Wistar Rats
Subject Areas : biology
Keywords: Streptozotocin, Rat, Satureja rechingeri, Diabetes,
Abstract :
The prevalence of diabetes in word is rapidly rising.Stress oxidative is risk factors in diabetes. . If untreated, it is complications ,such as atherosclerosis , ophthalmic complication ,retinopathy and cardiovascular complications, nephropathy, disability and death.Satureja rechingeri essence has antioxidant effects.The aim of this study was effect Satureja rechingeri essence on treating diabetes in diabetic male wistar rats.The study was carried out on 30 male rats.Male rats were divided into three groups randomly,group one as control,group two diabetic untreated, group three diabetic treated with Satureja-rechingeri essence by injection 100 mg/kg ,i.p .Diabetes was induced inthe second and third groups by injection 60 mg/kg ,i.p of streptozotocin .After 3 weeks ,the serum levels of glucose،triglyceride(TG), cholesterol (C), LDL ,VLDL ,HDL of all groups were analyzed. The serum levels of glucose, triglyceride (TG), cholesterol(C)low density lipoprotein (LDL),very low density lipoprotein (VLDL) decreased in treated groups significantly.The levels of high densitylipoprotein (HDL) increased in treated groups significantly. This study showed that Satureja rechingeri essence effect on treating diabetes in diabetic rats.