The comparison of concentration in-vitro effects of Zataria multiflora Boiss and Mentha pulegium Essential Oil plants Composition with one of them Nystatin on Candida albicans Isolates of Vaginal Candidiasis and comparing their with standard
Subject Areas : biology
soaieh mansoori
1
(نویسنده مقاله)
محمد دخیلی
2
(نویسنده مقاله و عهده دار مکاتبات)
محسن زرگر
3
(نویسنده و عهده دار مکاتبات)
Keywords: Antifungal, Mentha pulegium Essential Oil, Zataria multiflora Boiss Essential Oil, Nystatin,
Abstract :
Background & Objective: Candidal vulvovaginitis occurs in female genital by the over growth of candida especially candida albicans. Noticing the daily increase of drug resistance, attempts should be made for providing anti-fungal and anti-microbial drugs. This study is to determine the comparison of concentration in-vitro effects of Zataria multiflora Boiss and Mentha pulegium Essential Oil plants Composition with one of them Nystatin on Candida albicans Isolates of Vaginal Candidiasis and comparing their with standard.Materials and Methods : This experimental study assessed the antimicrobial effect of 2 plant extracts on Candida Albicans. Zataria multiflora Boiss and Mentha pulegium were selected based on previous researches and traditional usel. On each plate, one plant extract disc, one nystatin disc (aspositive control) and one blank disc (as negative controls) were placed. The mean diameter of non-growth halo around each plant extract was compared with the mean diameter of non-growth halo of positive control discs after 24 hours.Data analysis was done by ANOVA statistical test. Results: There was significant different between the diameter of non-growth halo around the plant extracts and nystation discs. (p<0.05). Conclusion: Zataria multiflora Boiss and Mentha pulegium exhibited antifungal effects on C. Albincans But the effect of Mentha pulegium on the lack of growth of Candida Albicans strains was greater than that in Zataria multiflora Boiss.