Effect of high intensity exercise training on salivary levels of lysozyme, LL-37 and HBD-2 in obese adolescent boys
Effect of exercise g on salivary lysozyme, LL-37 and HBD-2
Subject Areas : Experimental physiology and pathology
Behrouz Alizadeh Qale Zawarq 1 , Farzad Zahsaz 2 * , Karim Azali Alamdari 3 , Akbar Moin 4
1 - Department of Physical Education, Tabriz Branch, Islamic Azad University, Tabriz, Iran
2 - Department of Physical Education, Tabriz Branch, Islamic Azad University, Tabriz, Iran
3 - Department of Sports Sciences, Faculty of Educational Sciences and Psychology, Shahid Madani University of Azerbaijan, Tabriz, Iran
4 - Department of Physical Education, Sardroud Branch, Islamic Azad University, Sardroud, Iran
Keywords: LL-37", HDB-2", ", Lysozyme", exhaustive exercise", overweight Boy",
Abstract :
Background &Aim: Wellness requires the proper functioning of the immune system in all of the body systems. The immune system active by the cooperation of several immune sections. The immune cells and substances can identify and destroy foreign viral and microbial agents that worn out cells and cancer cells in the body. The aim of this study was to investigate the effect of high-speed sports activity on the anti-inflammatory factors lysozyme, LL-37 and HDB-2 in the saliva of obese adolescent boys. Materials &Methods: 32 male students voluntarily participated in the present study and were randomly assigned to four groups: 1) obese aerobic exercise, 2) normal weight aerobic exercise, 3) obese control without exercise, and 4) normal weight control without exercise. Anthropometric indices of height, weight and body mass index were measured. Before and after eight weeks of practice, Shatell-Run standard test was performed. Salivary samples of lysozyme, lactoferrin, lactate and C-reactive protein concentrations were taken after eight weeks of training with a frequency of three sessions per week with an intensity of 30 to 90% of maximum aerobic power. Using analysis of covariance, variables with a significance level of less than (p≥0.05) were included in the analysis. Results: The results showed that the salivary levels of lysozyme (p=0.001), LL-37 (p=0.002), and HDB2 (p=0.001) increased significantly, and the amount of increase in obese students was higher than in people with normal weight. Conclusion: The increased response of some salivary anti-inflammatory proteins following eight weeks of high-speed exercise training after increased activity may be due to the short-term responses of the immune system against the pressures caused by intense activity.
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