Effect of Spirulina platensis on Testicular Tissue Structure and Sex Hormones inMale Mice

Subject Areas :

Akbar Karimi ¹ , Mahbubeh Ziaei ²

1 - استادیار گروه زیست شناسی، دانشگاه پیام نور تهران، تهران. ایران.
2 - کارشناسی ارشد گروه زیست شناسی، دانشگاه پیام نور تهران، تهران. ایران.

Received: 2016-11-01 Accepted : 2018-08-04 Published : 2016-10-22

Keywords: Spirulina platensis, Testis, Spermatogenesis, Testosterone,

Abstract :

Inroduction & Objective:Spirulina platensis is a blue-green algae that has antioxidant and anti-inflammatory compounds. In this study the effects of Spirulina platensis on spermatogenesis in male mice was investigatedMethods40 mice were randomly divided into 4 groups(n=10), Control: normal saline, Experimental 1: 75 mg/kg, experimental 2: 150 mg/kg and experimental 3: 300 mg/kg of Spirulina platensisreceived via gavage(During treatment= 30 days, every other day). After treatment the right testis of mice removed and fixed. The tissue stained with H&E. In tissues lineage cells of spermatids , epithelial thickness measured. Levels of testosterone , FSH and LH checked out. Data were analyzed with ANOVA and Duncan test. Level significant was pResultsThe number of spermatogonia , spermatocytes , epithelial thickness and level of testosterone, FSH and LH in experimental 3 increased significant compared with control groupConclusionSpirulina platensisconsumption in male mice increase the number of spermatids , FSH and testosterone