The effect of eight weeks of aerobic training on VO2max and BMI of overweight and obese women in different types of NRF1 and NRF2 genotypes

Subject Areas : Physical Activity and Health

Maryam  Kamari ¹ (Department of Physical Education, Faculty of Humanities, Islamic Azad University, Borujerd Branch, Borujerd, Iran)
Masoud  Rahmati ² (Department of Physical Education and Sport Sciences, Faculty of Literature and Human Sciences, Lorestan University, Khoramabad, Iran)
Mehdi  Boostani ³ (Department of Physical Education, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran)

Received: 2023-11-30 Accepted : 2023-12-22 Published : 2023-10-23

Keywords: NRF, VO2max, Aerobic training, Body Mass Index,

Abstract :

Aim: The purpose of this study was to determine the effect of eight weeks of aerobic training on VO2max and BMI of overweight and obese women in different types of NRF1 and NRF2 genotypes.Methods: 23 inactive obese women (30-45 years old, body mass index>30) voluntarily and purposefully participated in the research. At the beginning of the research the subjects participated in an aerobic training program for eight weeks. Measurements related to height, weight, body mass index and VO2max of the subjects were done before and after the training program. 24 hours after completing the training program, in order to extract DNA and observation of genetic profile by RFLP method, saliva samples were collected in special kits. Subjects were placed in three genotypic groups AA, AC and CC for NRF1 and one genotypic group AA for NRF2. To check the frequency of genotypes Chi-square statistical test and one-way ANOVA test and dependent T-test were used to check the difference between variables.Results: The results of analysis related to NRF1 gene showed that there is non-significant difference in VO2max (p=0.854 and F=0.159) and body mass index (p=0.956 and F=0.036) between groups. Also, the results related to the NRF2 gene showed that the subjects' VO2max increased significantly after eight weeks of aerobic training (p=0.001).Conclusion: The present study showed that only in the NRF2 AA genotype, the endurance capacity of subjects increases due to aerobic exercise.