Fabrication of non-metallic Polycaprolactone-Baghdadite nanoparticles plates for using in repairing of bone damages

Subject Areas :

حسین عمادی ¹ , Mahdi Karevan ²

1 - دانشگاه صنعتی اصفهان
2 - Assistant Professor, Department of Mechanical Engineering, Isfahan University of Technology, Isfahan, Iran

Received: 2017-04-15 Accepted : 2019-03-04 Published : 2019-02-20

Keywords: nanocomposite, Morphological properties, biological properties, Polycaprolactone, Baghdadite,

Abstract :

Metal bone plates are used to stabilize bone fractures in orthopedic surgical treatment for years. The differences between stiffness of Metal plates and bone lead to osteoporosis and increase the risk of again fractures in the area of the plate. In addition, wear and corrosion of metal plaques lead to release of unwanted corrosion products in the body. To fix this problem ceramic polymer degradable composites can be used. The purpose of this research was to fabricate non-degradable bone plate of Polycaprolactone-Baghdadite (Ca3ZrSi2O9) to stabilize and restore the bone tissue damages. Polycaprolactone (PCL) is semi-crystalline polymer with biocompatible body, but the degradation rate of PCL than other biocompatible polymer is lower and has higher fracture energy. Baghdadite is a bioceramic with high bioactivity properties, so the additions of baghdadite nanoparticles to PCL lead to increase the bioactive of PCL meanwhile improve the speed of degradation of the composites. In this study, Baghdadite powder was prepared by the sol-gel method and then values of 0, 10 and 20 wt% nano-powder added to PCL. In order to evaluate the biological properties, the test of immersion in (SBF) applied and assessment of particle shape and morphology of samples was done by scanning electron microscopy. Tensile test used to determine the mechanical properties. The results showed that the Baghdadite powder composed with average particle size of 30 nm, While have the proper distribution and uniformity in the polymer matrix; subjoin it to matrix phase lead to increased biological and strength properties of the composite.

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