Survey on immunogenicity effcacy of a dual vaccine, Combined Rev. 1 and Sheep Pox Vaccine

Subject Areas : clinical veterinary science

احسان Gharib Mambini, ¹ , , M. Gharib Mambini ² , مراد Moradi Maravand, ³ , A. Rezaie ⁴ , محسن Mashkuh, ⁵ , مصطفی Kenarkuhi, ⁶ , داراب Abdolahi, ⁷ , , K Amiri ⁸ , محمد Antikchi, ⁹ , افشین Gharib Mambini, ¹⁰ , N. Soltanisedeh, ¹¹

1 - Faculty Of Veterinary Medicine, Shahid Chamran Ahvaz University
2 - اداره مبارزه با بیماریهای دامی، اداره کل دامپزشکی استان خوزستان
3 - رئیس گروه بیماریهای میکروبی و سل گاوی، سازمان دامپزشکی کشور
4 - مدیر کل بهداشت و مدیریت بیماریهای دامی، سازمان دامپزشکی کشور
5 - معاونت بهداشتی و پیشگیری، سازمان دامپزشکی کشور
6 - مدیر کل دامپزشکی استان خوزستان
7 - رئیس گروه بیماریهای ویروسی سازمان دامپزشکی کشور
8 - رئیس گروه کنترل بیماری بروسلوزیس، سازمان دامپزشکی کشور
9 - کارشناس مبارزه با بیماریهای دامی، اداره کل دامپزشکی استان خوزستان
10 - دانشکده مهندسی، دانشگاه شهید چمران اهواز
11 - دانشکده پزشکی، دانشگاه جندی شاپور اهواز

Received: 2016-11-04 Accepted : 2016-11-04 Published : 2014-03-21

Keywords: Vaccine, Brucellosis, Sheep pox, Agglutination Test, Mercapto Ethanol,

Abstract :

The diseases, brucellosis and sheep pox, are endemic in Iran and they cause serious losses to the production andhealth of livestock. Susceptible livestock have been vaccinated against these two diseases in appropriate seasonswith a vaccine from Razi Institute vaccine for several years. But these diseases, especially the dangerous zoonosisbrucellosis, have not been eradicated after all these years. In this case-control study, 40 lambs within the age rangeof 3.5 - 6 months were selected from a native sheep flock. Vaccines and materials used in this survey were obtainedfrom Razi Institute. This study revealed that the administration of dual vaccine contained of bacterial vaccinesFDRev. 1 with sheep pox vaccine with one injection produced antibody titration as the same as FDRev.1 vaccineseparately. It would be cost beneft to conduct this research for the whole country as it will save lots of money inthe context of staff administration and vaccination. It can also decrease the side effects of multiple vaccinationssuch as stress.