Rapid diagnosis of different mycobacterial species in Tuberculosis
Subject Areas : clinical veterinary science, E Jabbarzadeh 1 , مهناز Saif, 2
1 - Department of Mycobacteriology, Pasteur Institute of Iran
2 - Department of Mycobacteriology, Pasteur Institute of Iran
Keywords: Tuberculosis, Mycobacterium, Rapid Detection,
Abstract :
Transmition of tuberculosis between man and livestock is quite common. In the world tuberculosis is describedto be present in 20 million people. and every year 5 million people is added to this fgure. People living in poorerareas are more in danger of the tuberculosis. Tuberculosis has been diagnosed in cows with dilapidated tuberclesin various organs. In addition to the cow, man, goats and pigs are sensitive to bovine tuberculosis, sheep and horsesshow a kind of natural resistance.Three types of Mycobacterium tubercule bacilli have been recognized among warm blooded animals , whichhuman tuberculosis species (Mycobacterium tuberculosis) and bovine species (Mycobacterium bovis) are verysimilar to each other but a kind of chicken species is different.Identifcation of different mycobacterial species with biochemical and phenotypic methods is time-consumingand diffcult, and using these diagnostic methods created some problems to identify some of these species. Todayrapid molecular diagnostic methods for mycobacterial species which infected human communities have importantposition in epidemiology and control of tuberculosis. Therefore, the recognition of the strain types in every regionreveals the usefull information about the disease for every society. This issue in identifying all cases infected withthe mycobacterial strains (Atypical and TB) is very important.Recently some techniques such as Restriction Fragment Length Polymorphism (RFLP) and the use of specifcprobes in the diagnosis of mycobacterial strains have much effciency. By using these methods one can easily takesamples from suspicious humans or animals and in one mycobacterial infection and species identifcation can beperformed. It is obvious that quick diagnosis of mycobacterial infections can help to reduce the disease in thecountry.