The changes in the fibrinogen concentration and coagulation pathways in winter and summer in cattle

Subject Areas : Veterinary Clinical Pathology

ameneh  khoshvaghti ¹ (دانشگاه آزاد اسلامی، واحد کازرون، دانشکده دامپزشکی، گروه علوم درمانگاهی، کازرون، ایران.)

Received: 2013-07-01 Accepted : 2013-10-28 Published : 2013-08-23

Keywords: Fibrinogen, Cow, Activated partial thromboplastin time, Prothrombin time,

Abstract :

   Fibrinogen is an important coagulation factor and a positive acute phase protein and its levels increases in cases of inflammation infection and stress. The present research was done to determine whether the fibrinogen concentration, prothrombin time (PT) and activated partial thromboplastin time (APTT) can be affected by seasonal changes. In this study, the blood of ten apparently healthy cows from around Yasouj city were taken under aseptic conditions and, then the plasma was separated. The fibrinogen concentration, was assayed by sedimentation refractometry method, PT and APTT were measurement by coagolometric method. The statistical analysis indicated that there was significant difference between the mean concentration of fibrinogen in summer and winter (P<0.05), but the increase in PT and APTT was not as much that a significant statistical difference could be seen between these parameters in winter and summer (P>0.05). It is concluded that seasonal changes can affect the fibrinogen concentration but does no affect PT and APTT significantly.

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