The effect of different concentrations of bee propolis on skin wound healing and immune response and survival of Common carp (Cyprinus carpio)
Subject Areas : Veterinary Clinical Pathologynasrin choubkar 1 * , abbasali sari 2 , alireza bolandnazar 3 , hashem heshmati 4 , forough mohammadi 5 , nastaran shahbazian 6 , amirmohammad emamirad 7 , payam yari 8
1 - دانشگاه آزاد اسلامی، واحد کرمانشاه، دانشکده کشاورزی، گروه شیلات، کرمانشاه، ایران.
2 - دانشگاه بوعلی سینا، گروه پیراپزشکی، همدان، ایران.
3 - موسسه تحقیقات باریج اسانس، کاشان، ایران.
4 - دانشگاه علوم پزشکی گلستان، گروه بهداشت، گرگان، ایران.
5 - دانشگاه آزاد اسلامی، واحد کرمانشاه، دانشکده کشاورزی، گروه دامپزشکی، کرمانشاه، ایران.
6 - اداره دامپزشکی، بخش بهداشت آبزیان، کرمانشاه، ایران.
7 - دانشگاه پیام نور، گروه مهندسی شیمی، تهران، ایران.
8 - کارشناسی ارشد شیلات، اهواز، ایران.
Keywords: Propolis, immune system, Common carp, Wound healing, Survival,
Abstract :
Antibiotics use to increase the immune and wound healing in many animals. But due to the residual effects of a drug, Antibiotics and used to increase the immune response and propolis wound healing is aquadic animals. But due to their residual, researchers are looking to replace them with natural materials. One of these natural materials that has many health benefits is bee propolis. The aim of this study was to evaluate the effect of different concentrations of propolis on wound healing and immune system response in common carp (Cyprinus carpio). Propolis extracts were prepared from Kashan Barij essence with different concentrations of 0 , 2 , 5 and 10% with carrier substances (to dissolve the propolis in water), and were evaluated on wound healing and immune response and survival of common carp on a 21 –day cycle of short baths once a day . The results showed that, compared with the control group (0%), the use of bee propolis in concentration of 2% has statistically significant difference on wound healing and immune system response in common carp. The use of higher concentrations of propolis healed wound, but increased the number of blood cells (red blood cells, neutrophils, and eosinophils) and increased mortality of fish, so it is better to use lower concentrations of propolis in fish. The use bee propolis as additive in water is effective in low concentrations and stimulates the immune system.