Assessment of the effect of co- administration of Aloe vera gel and Fenugreek seed hydroethanolic extract on the improvement of full-thickness excisional skin wound healing in diabetic mice
Subject Areas :
Veterinary Clinical Pathology
mohamadreza farahpour
1
,
mohammad Aghaei
2
1 - استادیار گروه علوم درمانگاهی، واحد ارومیه، دانشگاه آزاد اسلامی، ارومیه، ایران.
2 - دانشجوی دکتری، گروه علوم باغبانی، دانشکده کشاورزی، دانشگاه ارومیه، ارومیه، ایران.
Received: 2015-11-22
Accepted : 2016-01-30
Published : 2016-01-21
Keywords:
References:
Atiba, A., Ueno, H. and Uzuka, Y. (2011). The effect of aloe vera oral administration on cutaneous wound healing in type 2 diabetic rats. Journal of Veterinary Medical Science, 73(5): 583-589.
Beldon, P. (2010). Basic science of wound healing. Surgery (Oxford), 28(9): 409-412.
Bin-Hafeez, B., Haque, R., Parvez, S., Pandey, S., Sayeed, I. and Raisuddin, S. (2003). Immunomodulatory effects of fenugreek (Trigonella foenum graecum L.) extract in mice. International immunopharmacology, 3(2): 257-265.
Bukhari, S.B., Bhanger, M.I. and Memon, S. (2008). Antioxidative Activity of Extracts from Fenugreek. Pakistan Journal of Analytical and Environmental Chemistry, 9(2): 78-83.
Choi, S.W., Son, B.W., Son, Y.S., Park, Y.I., Lee, S.K. and Chung, M.H. (2001). The wound‐healing effect of a glycoprotein fraction isolated from aloe vera. British Journal of Dermatology, 145(4): 535-545.
Eseyin, O.A., Ebong, P., Ekpo, A., Igboasoiyi, A. and Oforah, E. (2007). Hypoglycemic effect of the seed extract of Telfairia occidentalis in rat. Pakistan Journal of Biological Sciences, 10(3): 498-501.
Farahpour, M. and Habibi, M. (2012). Evaluation of the wound healing activity of an ethanolic extract of Ceylon cinnamon in mice. Veterinarni Medicina, 57(1): 53-57.
Farahpour, M.R., Mirzakhani, N., Doostmohammadi, J. and Ebrahimzadeh, M. (2015). Hydroethanolic Pistacia atlantica hulls extract improved wound healing process; evidence for mast cells infiltration, angiogenesis and RNA stability. International Journal of Surgery, 17: 88-98.
Folkman, J. (1995). Angiogenesis in cancer, vascular, rheumatoid and other disease. Natural Medicine, 1(1): 27-31.
Gabir, M.M., Hanson, R.L., Dabelea, D., Imperatore, G.I.U.S.E.P.P.I.N.A., Roumain, J.A.N.I.N.E., Bennett, P.H., et al. (2000). Plasma glucose and prediction of microvascular disease and mortality: evaluation of 1997 American Diabetes Association and 1999 World Health Organization criteria for diagnosis of diabetes. Diabetes care, 23(8): 1113-1118.
Kawabata, T., Cui, M.Y., Hasegawa, T., Takano, F. and Ohta, T. (2011). Anti-inflammatory and anti-melanogenic steroidal saponin glycosides from Fenugreek (Trigonella foenum-graecum L.) seeds. Planta Medica, 77(7): 705-710.
Hamman, J.H. (2008). Composition and applications of Aloe vera leaf gel. Molecules, 13(8): 1599-1616.
Hardwicke, J.T., Hart, J., Bell, A., Duncan, R., Thomas, D.W. and Moseley, R. (2011). The effect of dextrin–rhEGF on the healing of full-thickness, excisional wounds in the (db/db) diabetic mouse. Journal of Controlled Release, 152(3): 411-417.
Hu, Y., Xu, J. and Hu, Q. (2003). Evaluation of antioxidant potential of Aloe vera (Aloe barbadensis Miller) extracts. Journal of Agricultural and Food Chemistry, 51(26): 7788-7791.
Langmead, L., Makins, R.J. and Rampton, D.S. (2004). Anti‐inflammatory effects of aloe vera gel in human colorectal mucosa in vitro. Alimentary Pharmacology and Therapeutics, 19(5): 521-527.
Maenthaisong, R., Chaiyakunapruk, N., Niruntraporn, S. and Kongkaew, C. (2007). The efficacy of aloe vera used for burn wound healing: a systematic review. Burns, 33(6): 713-718.
Mandegary, A., Pournamdari, M., Sharififar, F., Pournourmohammadi, S., Fardiar, R. and Shooli, S. (2012). Alkaloid and flavonoid rich fractions of fenugreek seeds (Trigonella foenum-graecum L.) with antinociceptive and anti-inflammatory effects. Food and Chemical Toxicology, 50(7): 2503-2507.
Moghbel, A., Ghalambor, A. and Allipanah, S. (2007). Wound healing and toxicity evaluation of Aloe vera cream on outpatients with second degree burns. Iranian Journal of Pharmaceutical Sciences, 3(3): 157-160.
Ozay, Y., Ozyurt, S., Guzel, S., Cimbiz, A., Olgun, E.G. and Cayci, M. (2010). Effects of Equisetum arvense Ointment on Dermal Wound Healing in Rats. Wounds, 22(10): 261-267.
Pandian, S., Anuradha, C. and Viswanathan, P. (2002). Gastroprotective effect of fenugreek seeds (Trigonella foenum-graecum) on experimental gastric ulcer in rats. Journal of Ethnopharmacology, 81(3): 393-397.
Papanas, N. and Maltezos, E. (2011). Polyherbal formulation as a therapeutic option to improve wound healing in the diabetic foot. The Indian Journal of Medical Research, 134(2): 146-151.
Rajasekaran, S., Sivagnanam, K. and Subramanian, S. (2005). Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in rats. Pharmacology Report, 57(1): 90-96.
Reuter, J., Jocher, A., Stump, J., Grossjohann, B., Franke, G. and Schempp, C.M. (2008). Investigation of the anti-inflammatory potential of Aloe vera gel (97.5%) in the ultraviolet erythema test. Skin Pharmacology and Physiology, 21(2): 106-110.
Sharififar, F., Khazaeli, P. and Alli, N. (2009). In vivo evaluation of anti-inflammatory activity of topical preparations from Fenugreek (Trigonella foenum-graecum L.) seeds in a cream base. Iranian Journal of Pharmaceutical Sciences, 5(3): 157-162.
Visuthikosol, V., Chowchuen, B., Sukwanarat, Y., Sriurairatana, S. and Boonpucknavig, V. (1995). Effect of Aloe vera gel to healing of burn wound a clinical and histologic study. Journal of Medicine Association of Thailand, 78(8): 403-409.
Xue, W.L., Li, X.S., Zhang, J., Liu, Y.H., Wang, Z.L. and Zhang, R.J. (2007). Effect of Trigonella foenum-graecum (fenugreek) extract on blood glucose, blood lipid and hemorheological properties in streptozotocin-induced diabetic rats. Asian Pacific Journal of Clinical Nutrrition, 16(1): 422-426.
