Determining drug resistance patterns of Clostridium perfringens isolates from acute necrotic enteritis (NE) outbreaks

Subject Areas : Veterinary Clinical Pathology

حسین نیک‌پیران ^{1 *} , بهرام شجاع‌دوست ² , سیّد مصطفی پیغمبری ³

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Accepted : 2008-07-17 Published : 2008-02-20

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Abstract :

     In this study, after separating 40 Clostridium perfringens isolates from affected broiler flocks, the antibacterial susceptibility test revealed 39 drug resistance patterns in which 95% of the isolates were distributed into 38 different patterns (one isolate in each pattern) and only 5% of the isolates were placed in a single pattern (two isolates in a pattern). All 40 Clostridium perfringens isolates demonstrated resistance to chloramphenicol, vancomycin and sulfamethoxazole+trimethoprime, ranging from 0 to 17.5% while tetracycline, lincomycin and neomycin sulfate had a high level of resistance from 80 to 87.5%. Also an isolate demonstrated multiple resistance to more than 14 antibacterial compounds.