Comparison of the effect of Microvit supplementation and Ferrodrop oral drop on primary parameters of hemogram and serum minerals in 20-day-old healthy and Pica affected lambs

Subject Areas : Veterinary Clinical Pathology

Samad Lotfollahzadeh ¹ , Mostafa Abdollahi ² , Parviz Noshirvani ³ , Hamidreza Mohammadi ⁴ , Morteza Abdollahi ⁵

1 - Associate Professor, Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
2 - Resident of Large Animal Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
3 - Resident of Veterinary Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
4 - Assistant Professor, Department of Clinical Science, Faculty of Veterinary Medicine, University of Semnan, Semnan, Iran.
5 - D.V.M Graduate, Faculty of Veterinary Medicine, Islamic Azad University, Garmsar Branch, Garmsar, Iran.

Received: 2018-10-05 Accepted : 2019-05-13 Published : 2020-04-20

Keywords: lamb, iron deficiency, Hemogram, pica, Oral supplementation,

Abstract :

Pica is one of the disorders that have high potential for inducing various damages such as poisoning, digestive accumulation, botulism, weight loss and etc. in ruminant farms. The present study was conducted to compare the effect of Microvit supplementation and Ferrodrop oral drops on the primary parameters of hemogram and serum minerals in 20-day-old healthy and Pica affected lambs.This study was performed on ten 20-day-old mixed-breed lambs without Pica and ten 20-day-old mixed breed lambs with Pica. Both groups received 2 types of oral therapy including Microvit supplementation (7 days, 0/5 g / l of consuming water) and oral ferrodrop drops (4 days, 300 mg/day in consuming milk). Before starting the treatment and after each treatment, blood samples were taken from the lambs to determine complete blood cell count (CBC) and serum minerals. Data were analyzed by SPSS statistical software using repeated measures ANOVA and post hoc Tukey test at 95% confidence level.In patients with Pica, blood Hb, MCV and MCHC and serum iron was significantly less than healthy lambs (p < /em><0/05). Treatment with Microvit did not increase the blood Hb, MCV and MCHC and serum iron levels significantly and Pica was not treated in patients. Treatment with ferrodrop increased the blood Hb, MCV and MCHC and serum iron levels significantly and Pica was treated in patients (p < /em><0/05). This study showed that the cause of Pica in suckling lambs was microcytic-hypochromic anemia due to iron deficiency and administration of 300 mg of ferrodrop oral drops for 4 days caused the treatment of the patients.

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