Water as a green solvent for fast and efficient synthesis of 1,5-benzodiazepines at room temperature by using Water-Tolerant Sulfonic Acid Nanoreactor Based on Tunable Ordered Porous Silica
GHolam Hossein Mahdavinia
1
(
Department of Chemistry, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
)
Soheila Ghassamipour
2
(
Department of Chemistry, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
)
Keywords: ZrOCl2.8H2O on Montmorillonite K10, MCM-41-SO3H , Heterogeneous catalyst, 1, 5-benzodiazepines,
Abstract :
A rapid and new green synthesis of 1,5-Benzodiazepines is reported. The title compounds were prepared by the reaction of different 1,2-phenylenediamines and ketones in the presence of ZrOCl2.8H2O on montmorillonite K10 and MCM-41-SO3H as a nanocatalyst in water. These methods are simple, effective, better yield and environmentally friendly. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .