Synthesis and antimicrobial activity of some novel heterocycles containing thiazole, oxazole, thiazine, oxazine and triazole moiety

Subject Areas : Journal of the Iranian Chemical Research

Vijay V. Dabholkar ¹ , Sunil R. Patil ² , Rajesh V. Pandey ³

1 - Organic Research Laboratory, Department of Chemistry, KC College, Churchgate, Mumbai, India
2 - Organic Research Laboratory, Department of Chemistry, KC College, Churchgate, Mumbai, India
3 - Organic Research Laboratory, Department of Chemistry, KC College, Churchgate, Mumbai, India

Received: 2010-12-25 Accepted : 2011-03-12 Published : 2011-03-20

Keywords: Monobromoindandione, Thiocarbamide, Carbamide, 2-Aminothiophenol, 2-Aminophenol, triazole,

Abstract :

Indandione 1 was brominated to yield 2-bromoIndandione 2 which on further reacted with substituted thiocarbamides, carbamides, 2-aminothiophenols, 2-aminophenol and triazoles to furnished 3-substituted aniline-2-thia-4-aza-6,7-benzo-8-oxo-bicyclo [3.3.0]-1(5),3-octadiene 3, 3-substituted aniline-2-oxa-4-aza-6,7-benzo-8-oxo-bicyclo [3.3.0]-1(5),3-octadiene 4, 2-Thia-5-aza-9-oxo-3,4-(3’-substituted) benzo-7,8-benzo-bicyclo [4.3.0]-1(6) nonene 5, 2-oxa-5-aza-9-oxo-(3, 4)-(7, 8)-dibenzo-bicyclo [4.3.0]-1(6) nonene 6, 3-substituted-(1,2,4) triazolo [4,5-b] [indeno (2,3-e)]-1,3,4-thiadiazine 7 respectively.

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