Sub-lethal effects of nano zinc oxide (ZnO NPs) on some hematological indices of goldfish (Carassius auratus)

Subject Areas : environmental management

Seyed Aliakbar  Hedayati ¹ (Assistant Professor of Marine Biology, Faculty of Fishery and Environment, Gorgan University of Agricultural Science and Natural Resources, Gorgan, Iran*(Corresponding Author))
Abdolreza  Jahanbakhshi ² (PhD of Fisheries Sciences, Faculty of Fishery and Environment, Gorgan University of Agricultural Science and Natural Resources, Gorgan, Iran)

Received: 2015-01-20 Accepted : 2015-11-16 Published : 2017-03-21

Keywords: Goldfish, hematology, nano-toxicology, Pollution,

Abstract :

Background and Objective: Extensive development of nanotechnology and applications of nano-particles in different industries has caused devastating effects of nano-materials on organisms. This study aimed to evaluate the effects of nano zinc oxide on hematological factors of goldfish. Methods: In this paper we determine the range of concentrations of zinc oxide nano-particles to determine LC50 of gold fish at 24, 48, 72 and 96 hours respectively. Then, according to the LC50, separate experiments were designed to induce sub-lethal concentration of this substance on Hematological parameters were studied. Blood samples of goldfish fry were taken in the 7 days following exposure to lethal concentrations (50% concentration) of nano-ZnO nano-materials with fish that were not exposed. Findings: The results showed that the nano-particles could changes in blood parameters of gold fish by increasing red blood cell (RBC), hemoglobin, hematocrit, MCV in treatment was influenced by the nano-particles, was (P>0.05) and reduced white blood cell (WBC) in the treatment of fish exposed to lethal concentrations of nano-particles compared to the control group (P>0.05) but did not show significant change in MCH, MCHC indices. Discussion and Conclusions: In conclusion sub-lethal concentration of nano zinc oxide could affect hematological parameters of goldfish and this fish have more resistance to this kind of pollutant. 

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