Tracking the Effect of Ginger Supplementation on the Levels of the Anti-inflammatory Index IL_10 Following Progressive Resistance Training in Young Male Volleyball Players

Subject Areas : Physiology of exercise

Mehdi Daeizadeh ¹ , Valiallah Dabidi Roshan ^{2 *} , Rozita Fathi ³

1 - Department of Physical Education, Sar. C., Islamic Azad University, sari, Iran
2 - Department of Physical Education, Mazandaran University, Babolsar, Iran
3 - Department of Physical Education, Mazandaran University, Babolsar, Iran

Received: 2024-12-11 Accepted : 2024-12-29 Published : 2025-03-19

Keywords: Keywords: Ginger, Anti-inflammatory index, IL_10, resistance training, young male volleyball players,

Abstract :

Objective: Given that the anti-inflammatory effects of IL-10 and the anti-inflammatory efficacy of ginger supplementation have been reported in several studies, examining the values ​​of this index can answer some of the ambiguities in this field, especially the anti-inflammatory effect of using ginger supplementation as a non-pharmacological approach. Accordingly, the present study aimed to track the effect of ginger supplementation on the anti-inflammatory index IL_10 values ​​following incremental resistance training in young male volleyball players.

Methods: 40 young male volleyball players aged 17 to 22 years without any disease, musculoskeletal injury, and no history of weight training for at least the last six months were selected. Blood sampling from the subjects of the present study was performed during the research period in two stages before and after incremental resistance training with and without ginger supplementation or placebo under completely similar conditions. To study the effect of the incremental resistance training protocol or the effect of the supplement or placebo in each group at different stages, two-way analysis of variance was used in the measurements and the LSD post-hoc test at a significance level of P ≥ 0.05.

Results: According to the results of the LSD post-hoc test, it is observed that the changes in IL10 values ​​in the period before ginger supplementation following the implementation of the incremental resistance training protocol in the stages immediately after the completion of the incremental resistance training protocol and 24 hours after its completion are significant compared to the resting levels of the same period. (P value is equal to 0.000 and 0.001, respectively). On the other hand, the changes in the values ​​of this index following the implementation of the incremental resistance training protocol after one week of ginger supplementation in the stage immediately after its completion were significant, while in the stage 24 hours after the completion of the protocol compared to the resting levels of the same period (after ginger supplementation) are not significant. (P-values ​​are 0.001 and 0.081, respectively)).

Conclusions: Based on the overall results of the present study, it was determined that the aforementioned training method increased the values ​​of the anti-inflammatory index of interleukin 10 immediately and 24 hours later compared to the rest period. The changes in the values ​​of this index between groups were also not statistically significant in any of the stages before and after the supplementation period or resistance training, except for the immediate post-training phase in the post-supplementation period.

References:

دبیدي روشن، ولی الله؛ گائینی، عباسعلی ؛ ناموراصل، نبی الله .(1386) .تاثیر چهار هفته بی تمرینی بر پروتئین واکنش دهنده C- موشهاي صحرایی؛ المپیک سال پانزدهم، شماره (1)
طالب ، ام. (1381). فارما کوپه گیاهی ایران- کمیته تدوین، ص 387.
غضنفری هادی؛ موسوی سید رضا؛ وجگانی محمد؛ (1389) ایمونولوژی 4 استاد. چاپ پنجم.
کیانی، نجمه، رحیمی، اسکندر، حسینی، سیدعلی، و منصوری، زهرا. (1393). بررسی تاثیر هشت هفته تمرین مقاومتی برسطوح اینترلوکین- 10, لنفوسیت, مونوسیت و ماکروفاژ پسران 18-17 ساله. تحقیقات در علوم زیستی ورزشی، 4(13)، 39-50. SID. https://sid.ir/paper/240574/fa
AC, Vinci DM, Carson JA, Brown A, Lee WJ, McAnulty SR, and McAnulty LS.Carbohydrate.(2003). ingestion influences skeletal muscle cytokine mRNA and plasma cytokine levels after a 3-h run. J Appl Physiol 94: 1917-1925.
Fish DE, Krabak BJ, Johnson-Greene D, deLateur BJ.(2003). Optimal resistance training: Comparison of DeLorme with Oxford techniques. Am J Phys Med Rehabil 82:903–909.
Malm C, Nyberg P, Engstrom M, Sjodin B, Lenkei R, Ekblom B, and Lundberg I.(2000). Immunological changes in human skeletal muscle and blood after eccentric exercise and multiple biopsies. J Physiol 529: 243-262.
Miguel Soares Conceição • Cleiton Augusto Libardi • Felipe Romano Damas Nogueira.Effects of eccentric exercise on systemic concentrations of pro- and anti-inXammatory cytokines and prostaglandin (E2):
Ojewole JA.(2006). Analgesic, antiinflammatory and hypoglycaemic effects of ethanol extract of Zingiber officinale (Roscoe) rhizomes (Zingiberaceae) in mice and rats. Phytother Res. Sep;20(9):764-72.
Penna SC, Medeiros MV, Aimbire FS, Faria-Neto HC, Sertié JA, Lopes-Martins RA.(2003) Anti-inflammatory effect of the hydralcoholic extract of Zingiber officinale rhizomes on rat paw and skin edema. Phytomedicine.;10(5):3815.
Shimoda H, Shan SJ, Tanaka J, Seki A, Seo JW, Kasajima N, Tamura S, Ke Y, Murakami N.(2010) Anti-inflammatory properties of red ginger (Zingiber officinale var. Rubra) extract and suppression of nitric oxide production by its constituents. J Med Food. Feb;13(1):156-62.
Smith L.L.(2000) Cytokine hypothesis of overtraining: a physiological adaptation to excessive stress? Med. Sci.sports. Exerc. 32: 317-331.
Thomson M, Al-Qattan KK, Al-Sawan SM, Alnaqeeb MA, Khan I, Ali M.( 002) The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. ProstaglandinsLeukot Essent Fatty Acids. Dec;67(6):475-8