Phytochemical Study and Antifungal Effect of Essential Oil of Iranian Artemisia (Artemisia Persica Boiss.) in compare to synthetic Borneol against the Aspergillus niger

Subject Areas : Medicinal Plants

mohammad moghtader ¹ (Department of Biodiversity, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran)
hassan salari ² (Department of Ecology, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran)
hossein mozafari ³ (Department of Ecology, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran)
armita farahmand ⁴ (Department of Biotechnology, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran)

Received: 2018-01-14 Accepted : 2018-10-09 Published : 2018-11-22

Keywords: Antifungal, Aspergillus niger, Artemisia, Artemisia persica Boiss, Essential oil,

Abstract :

Essential Oil of Iranian Artemisia (Artemisia persica Boiss.) Contains essential oils with important secondary metabolites such as; borneol and 1,8-cineol and so these organic compounds have antimicrobial and antifungal properties. In this study, for determining of essential oil composition and antifungal effect of this oil, the aerial parts of Artemisia Persica Boiss. at pre-flowering stage (PF) were collected from Kerman region in June 1394. The essential oil was carried out by using Clevenger's apparatus by water distillation method and then was analyzed by GC/MS. The antifungal effect of essential oil against growth of Aspergillus strain was investigated by using The results were showed that the essential oil yield (v/w) was 1.55% from the 39 compounds which identified in plant essential oil, the borneol (32.8%), 1,8-cineol (18.3%), camphor (8.64%) and camphene (6.75%) were the main compounds of plant oil, respectively and the essential oil of plant with dilutions 1 and 1/2 has significant inhibitory power on the strain of Aspergillus niger in compare to the fluconazole antibiotic. The synthetic borneol with 10% dilution also had a significant inhibitory effect on Aspergillus Niger’s growth. The antifungal effects of essential oil can be attributed to the high percentage of borneol and 1,8-cineol present in it. According to these results it can be argued that the essential oil of this plant can be used as an herbal medicine with an appreciable antifungal effect, and also it’s could be used in various food, health and pharmaceutical industries.