Easy and efficient synthesis of 2-amino-4H-benzo[h]chromene derivatives in the presence of metformin and water solvent in ambient temperature
Subject Areas : Polymers and Organic StructuresAtieh Ahmadi 1 , Leila Moradi 2 *
1 - epartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, P.O. Box 8731753153, Kashan, Iran
2 - epartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, P.O. Box 8731753153, Kashan, Iran
Keywords: 1-Naphthol, Basic catalyst, Benzochromenes, Metformin, Green synthesis.,
Abstract :
In this research, in accordance with the development of green chemistry, various derivatives of 2-amino 4H-benzo[h]-chromene were synthesized using 1-naphthol, malononitrile and aromatic aldehydes in water solvent and in the presence of Metformin as homogeneous and basic catalyst at ambient temperature. All of products were obtained with high to excellent yields in duration of 5 to 20 minutes and all of derivatives were identified by FT-IR, 1H NMR and melting point characterization methods.
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