The Effect of Hydroalcoholic Extract of Passiflora caerulea Leaf on Some Biochemical Factors in Adult Male Rat
Subject Areas : Journal of Animal Biology
T. Sadeghi
1
(Department of Biology, Kazerourn Branch, Islamic Azad University, Kazerourn, Iran)
M. Shariati
2
(Department of Biology, Kazerourn Branch, Islamic Azad University, Kazerourn, Iran)
M. Mokhtari
3
(Department of Biology, Kazerourn Branch, Islamic Azad University, Kazerourn, Iran)
Keywords: Urea nitrogen, total protein, albumin, Creatinine, Passiflora Caerulea,
Abstract :
Passiflora caerulea is one of medicinal plants that has contained high anti-oxidant combinations and are useful in curing epilepsy, diarrhea, burn, Hemorrhoid and in regulating liver enzymes. The objective of this study was evaluation of effect of passiflora caerulea leaf hydroalcoholic extract on some biochemical factors in adult male rat. 40 male rats, about 195-200 g each were used in five groups. The control group did not receive any drug treatment, sham group found only distilled water, and experimental groups receiving 150,300,600, mg/kg leaves of passiflora caerulea Hydro-alcohol extract respectively during 21 days. After the end of this period, blood samples were taken from the heart to measure the biochemical factors (urea, creatinine, albumin, total protein). The results were analyzed using SPSS software and comparison of meanings was done using T. test. The results showed that the amount of albumin in the experimental group receiving 600 mg / kg of the extract decreased significantly compared to the control group. Total protein, cratinin and total body weight had no significant changes with control group. Hydro-alcoholic extracts of Passionate flower leaf caused reduction of blood urea nitrogen levels in all experimental groups receiving the extracts as compared to the control. According to the results of this study, it can be argued that the Passiflora caerulea plays a supporting role for the liver, and the lack of liver damage in the rats indicated this issue.
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