The Effect of Pomegranate Juice on Some Factors of Hemogram and Weight in Diabetic Mature Male Rats

Subject Areas : Journal of Animal Biology

سیدابراهیم حسینی ¹ , داود مهربانی ² , حمیدرضا قایدی ³

1 - دانشگاه آزاد اسلامی، واحد علوم و تحقیقات، گروه زیست‌شناسی، فارس، ایران
2 - دانشگاه آزاد اسلامی، واحد علوم و تحقیقات، گروه زیست‌شناسی، فارس، ایران
3 -

Received: 2014-06-21 Accepted : 2017-05-21 Published : 2013-10-23

Keywords: Diabetes, Male rat, Hemogram, Pomegranate juice,

Abstract :

Pomegranate juiceis an important source of antioxidant compounds and is a rich source of poly phenols, which are able to deal with the harmful effects of oxidation processes in tissues. Therefore, this study aimed to examine the effects of pomegranate juice on some factors of hemogram and weight in diabetic mature male rats.48 mature male rats were studied in the groups of normal control, sham and experimental, diabetic control, sham and experimental. The experimental groupsweredivided into three categories hadreceivedagavageamountsjuicewith1,2 and4 mldaily for21 days.The sham group received distilled water and the control group was not treated. At the end of21 dayswere bledfromthe heartventricle of the animalsandusing routinelaboratory were measuredthe total number ofwhite and red Globule blood, platelets, hemoglobin andhematocrit, meancell hemoglobinconcentration, meancellhemoglobin, MCVandweightchange. The data were evaluated usingANOVA, LSD and t test. The results showed that pomegranate juice can increase weight, number of white globule and volume of globule red, and decrease of platelets in mature male rats. The findings concluded that pomegranate juice probably due to antioxidant compounds and reduce stress hormones can increase white globule and weight and decrease platelets.