Phytochemical study of the Medicinal plant extract of (Rosa Canina L.) collected from Meshkin-shahr vegetation area and its antibacterial effect on common oral and dental bacteria.
Subject Areas : The Application of Chemistry in Environment
Hojjat Eghbal
1
(Department of Phytochemistry, Basic Sciences Research Center, Tabriz University, Iran.)
Mehdi Ahmadi Sabegh
2
(Department of Chemistry, Faculty of Basic Sciences, Islamic Azad University, Ahar Branch)
Keywords: HPLC, Antibacterial, Mountain Nestern, mouth and teeth,
Abstract :
Introduction and purpose: Recently, due to the increasing resistance of microorganisms to common antibiotics, the use of phenolic and antimicrobial compounds in medicinal plants has received special attention.Materials and methods: The extract of mountain nester plants was extracted by maceration method and their phenolic compounds were identified by HPLC, the antimicrobial effect of the extract was investigated in concentrations (25, 50 and 100 µg/ml). These bacteria included common microbes and fungi, including Streptococcus mutans, Streptococcus sanguinis, Streptococcus salivaris, Streptococcus subrinus, Escherichia coli, Icnella cordens, Pseudomonas aeruginosa and Klebsiella pneumoniae. Disc diffusion and MIC methods were used to investigate the antimicrobial activity of the extracts.Findings: In the investigation of the effect of each extract on bacteria, it was found that the medicinal plant of mountain nester has the least inhibitory effect against Klebsiella pneumoniae bacteria and the most inhibitory effect on Candida glabrata fungus. The results of the MIC test also confirm these effectsConclusion: According to the phytochemical results obtained from the extract of this research, it can be stated that the studied medicinal plant has antibacterial phenolic compounds. Therefore, the results of the research showed that the medicinal plant extract of mountain nasturtium has appropriate antimicrobial properties against bacteria that cause oral and dental infections, so this herbal medicine can be used as an alternative to standard chlorhexidine drugs. And Nystatin said.
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