The current study aims to know the role of low-density lipoprotein (LDL-C) on several variables, as well as its role in diagnosing some diseases by observing its metabolism processes in many diseases affecting humans and the imbalance, is significant in the level of this lipoprotein, which constitutes an essential factor of Risk factors for developing many diseases, especially cardiovascular disease. The present study aims at assessing the oxidized LDL role in pathogenesis. Manuscript profile