In this paper, an SIR epidemic model with an infectious period and a non-linear Beddington-DeAngelis type incidence rate function is considered. The dynamics of this model depend on the reproduction number R0. Accurately, if R0 < 1, we show the global asymptotic stability of the disease-free equilibrium by analyzing the corresponding characteristic equation and using comparison arguments. In contrast, if R0 > 1, we see that the disease-free equilibrium is unstable and the endemic equilibrium is permanent and locally asymptotically stable and we give sufficient conditions for the global asymptotic stability of the endemic equilibrium. Manuscript profile