A series of new coumarin fused pyrrole derivatives were successfully synthesized through a one-pot multi-component reaction between 4-aminocoumarin, aryl glyoxals, and amides (thioacetamide) in the presence of Fe3O4@SiO2/Kit-6 in ethanol under reflux conditions. Further advantages to this synthesis include excellent yields, mild reaction conditions, atom economy, environment-friendly, magnetically reusable catalyst, and no need for chromatographic separations. Manuscript profile

The interaction of acetaminophen drug by chitosan-capped gold Nanoparticles was investigated using a resonance Rayleigh scattering (RRS) spectroscopic technique. The standard deviation of (1.1 %), and detection limit of the method (0.5 ng mL-1 in time 6 min, 325 nm) were obtained for sensor level response chitosan-capped AuNPs with (97%) confidence evaluated. The results indicated that this method had good selectivity in the presence of coexisting compounds. The scattering intensity (ΔIRRS) was linearly dependent on acetaminophen drug concentration over the range (0.5 to 200.0 ng mL-1) with a determination coefficient (r) of 0.998. This method could be suitably used for analysis of acetaminophen drug in pharmaceutical, human fluid, and other drugs, and hospital samples. Manuscript profile

In this study, a one-pot and efficient method is reported for the synthesis of symmetrical disulfides from alkyl halides in the present of sulfur and 1-butyl-3-methylimidazolium hydroxide as a basic reagent and phase transfer catalyst. The reaction proceeded very fast and afforded the desired products in moderate to excellent isolated yields. Manuscript profile

In this project various types of carbonyl compounds were efficiently converted to their corresponding 1,3-oxathiolanes with 2-mercaptoethanol in the presence of catalytic amount of Al-MCM-41 with microwave energy. The catalyst can be reused several times without loss of its catalytic activity. Very short reaction times, reusability of the catalyst, and easy workup are noteworthy advantages of this method. Manuscript profile

In this study, a variety of 3, 4-dihydropyrimidin-2(1H)-ones derivatives were synthesized via three-component Biginelli reaction. The quaternary ammonium- treated clay -catalyzed process proved to be simple, efficient, and environmentally friendly. Manuscript profile

The reactive intermediate generated by the addition of tert-butyl and 1,1,3,3-tetramethyl butyl isocyanide and cyclohexyl isocyanide to dialkyl acetylenedicarboxylate was trapped by 3-hydroxy pyridine to produce highly functionalized 4H-chromenes in fairly good  yields Manuscript profile

In this study, a variety of 3, 4-dihydropyrimidin-2(1H)-ones derivatives were synthesized via three-component Biginelli reaction. The quaternary ammonium- treated clay -catalyzed process proved to be simple, efficient, and environmentally friendly. Manuscript profile

Caffeine loaded magnetic nanoparticle was successfully synthesized and were characterized by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray analysis (EDX), thermo gravimetric analysis (TGA), differential thermal analysis (DTA) and vibrating sample magnetometry (VSM). The resulting nanocomposite is shown to be an efficient catalyst in Knoevenagel condensations of various aldehydes under ultrasound irradiation.Caffeine loaded magnetic nanoparticle was successfully synthesized and were characterized by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray analysis (EDX), thermo gravimetric analysis (TGA), differential thermal analysis (DTA) and vibrating sample magnetometry (VSM). The resulting nanocomposite is shown to be an efficient catalyst in Knoevenagel condensations of various aldehydes under ultrasound irradiation.Caffeine loaded magnetic nanoparticle was successfully synthesized and were characterized by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray analysis (EDX), thermo gravimetric analysis (TGA), differential thermal analysis (DTA) and vibrating sample magnetometry (VSM). The resulting nanocomposite is shown to be an efficient catalyst in Knoevenagel condensations of various aldehydes under ultrasound irradiation. Manuscript profile

Caffeine loaded magnetic nanoparticle was successfully synthesized and were characterized by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray analysis (EDX), thermo gravimetric analysis (TGA), differential thermal analysis (DTA) and vibrating sample magnetometer (VSM). The resulting nanocomposite is shown to be an efficient catalyst in Knoevenagel condensation of various aldehydes under ultrasound irradiation. Manuscript profile

A novel magnetite nanoparticle-based heterogeneous acidic catalyst [Fe3O4@SiO2@Am-PPC-SO3H] [HSO4] was successfully prepared and characterized by SEM, EDX, TGA, VSM and FT-IR techniques. The magnetically retrievable and sustainable catalyst was investigated in the reaction of aldehyde and o-aminophenol for the synthesis of benzoxazoles. The reactions occurred in water and produced the corresponding products in high yields. The catalyst could be readily separated by an external magnet and showed excellent reusability without significant loss of its activity. Manuscript profile

HMCM-22 with a Si:Al molar ratio of 15:1 has been shown to effectively catalyze the synthesis of acetals with 100% selectivity by the reaction of aldehydes with methanol under reflux conditions. Platelet HMCM-22 particles were prepared by the static strategy and characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), BET techniques and N2-adsorption/desorption analysis. The catalyst was recovered by simple filtration and reused for several cycles without considerable loss of activity. HMCM-22 with a Si:Al molar ratio of 15:1 has been shown to effectively catalyze the synthesis of acetals by the reaction of aldehydes with methanol under reflux conditions. Platelet HMCM-22 particles were prepared by static method and characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), BET techniques and N2-adsorption/desorption analysis. The catalyst was recovered by simple filtration and reused for several cycles without considerable loss of activity. Manuscript profile

In this study, an efficient and green process for the synthesis of dihydropyrimidin-2(1H)-ones from aromatic benzaldehydes, ethyl acetoacetate and urea using Al-MCM-41 as heterogeneous catalyst and microreactor under solvent-free conditions has been developed. The advantages of this method are easy work-up procedure, regeneration of the catalyst, clean and neutral reaction conditions. Manuscript profile

Aromatic aldehydes are efficiently condensed with 2'-hydroxyacetophenone by polymer-supported basic ionic liquid as an excellent heterogeneous catalyst utilizing the Claisen–Schmidt reaction. Microwave irradiation has been employed, providing flavanone in good yield and short reaction time. Manuscript profile

In this study, aluminosilicate MCM-41 has been found to be an efficient catalyst for reaction betweendifferent benzaldehyde derivatives and 5,5-dimethyl-1,3-cyclohexanedione to give open chain analogue of1,8-dioxo-octahydroxanthene in excellent yields. No evidence for the formation of cyclization products wasobserved. The catalyst can be used several times after recovery. Manuscript profile