This research describes application of a mesoporous nanostructured material based on basic ionic liquid anchored to silica, i.e. nano-2-(dimethylamino)-N-(silica-n-propyl)-N,N-dimethylethanaminium chloride {nano-[DMSPDE][Cl]}, as a highly effective and heterogeneous nanocatalyst for the production of 2-amino-4H-chromenes. The one-pot multi-component reaction of aromatic aldehydes with malononitrile and 1-naphthol in the presence of nano-[DMSPDE][Cl] under solvent-free conditions affords the title compounds with high yields in short times. Manuscript profile

Lanthanum (III) oxide (La2O3) was applied as an efficient bifunctional catalyst to develop a new methodology in the production of 2-amino-4-aryl-4H-pyrans and pyrazolopyranopyrimidines in the absence of solvent. In both synthetic protocol, due to the dual functionality of lanthanum (III) oxide (i.e. having basic and acidic Lewis sites), it was very useful and general, and plausible mechanisms were presented in support of this generality and high capability. The current protocol featured environmentally friendly conditions, the ability to recycle and reuse the heterogeneous catalyst up to 6 times, providing products in short times with high yields, easy work-up and no need for difficult steps of catalyst synthesis by using a commercially available catalyst, which makes it an appealing route for the preparation of these derivatives. Manuscript profile