In this study, polyamide 6 (PA6)/ nitrile butadiene rubber (NBR) based hybrid-nanocomposites reinforced with calcium carbonate and organo-clay as nanofillers in various content of 1, 3 and 5 phr were prepared and characterized. The nanocomposite samples were prepared through the melt processing method in an internal mixer. The effect of rubber phase (NBR) content (10, 30, and 50 wt.%), calcium carbonate content (1, 3, and 5 phr), and organo-clay content (1, 3, and 5) was investigated on morphology and mechanical properties of the nanocomposites. The mechanical properties were evaluated by tensile, flexural, and Charpy impact tests. The results showed that adding the NBR reduces the tensile strength, tensile modulus, flexural strength, and flexural modulus, and increases the impact strength. Introducing the nano-clay and calcium carbonate improves the tensile and flexural strength, tensile and flexural modulus, and decreases the impact strength. The nano-clay content from 1 to 3 phr improved the impact strength. Manuscript profile