Abstract:Background: increasing body fat mass causes anemia. Exercising with the right type and intensity can improve iron status in people with extra fat mass. The aim of this study is to compare two different intensities of resistance training on hepcidin levels, iron status and body composition in obese/overweight girls. Method: 40 university students (18-22years old) with 35>BMI≥25 voluntarily participated in the study. Participants were divided into two groups of20, by blood sampling and based on serum ferritin (>30ng/ml or ≤30ng/ml). Subjects in each group were randomly assigned to one of the moderate or high-intensity training groups. Resistance training was performed 8 weeks, four days a week, and each session for one hour, with an elastic-band. body composition variables using specific tools, And the level of iron, hepcidin, TIBC, ferritin and hemoglobin was collected before and after exercise with the blood samples. Results: T-test showed, a significant decrease between pre-test and post-test in body composition variables, hepcidin and iron status variables of four groups other than hemoglobin. The analysis of variance of the bivariate showed a significant difference in hepcidin between the two groups with ferritin higher or lower than 30 ng/ml. The results of analysis of variance showed that there is a significant difference in hepcidin levels between the two groups with ferritin higher or lower than 30 ng/ml. Conclusion: resistance training with two different intensities can reduce hepcidin, ferritin and BMI in obese girls with and without iron deficiency and improve body composition. Baseline ferritin level seems to be effective on hepcidin levels after intervention. Keywords: resistance training, hepcidin, iron status, obesity Manuscript profile