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    1 - <i>Ammi visnaga</i> (L.) Lam.: An overview of phytochemistry and biological functionalities
    Trends in Phytochemical Research , Issue 3 , Year , Summer 2023
    Ammi visnaga (L.) Lam., (Apiaceae), known as” Bachnikha” or ”Khella” in Morocco, is one of the oldest and most important medicinal herbs native to the Mediterranean region of Asia, Europe, and North Africa. Several studies have reported its importance as a diuretic, ant More
    Ammi visnaga (L.) Lam., (Apiaceae), known as” Bachnikha” or ”Khella” in Morocco, is one of the oldest and most important medicinal herbs native to the Mediterranean region of Asia, Europe, and North Africa. Several studies have reported its importance as a diuretic, antiasthmatic, antipsoriasis, antioxidant, antifungal, antibacterial, vasodilator, and smooth muscle relaxant. These promising and valuable pharmacological effects result from a variety of important natural compounds constituting groups in the plant structure, e.g., γ-pyrones, coumarins, chromones, polyphenols, alkaloids, reducing compounds, cardiac glycosides, catechols, sterols, terpenes, quinones, mucilage, essential oil, C-heterosides, and O-heterosides. Within this framework, the current review was prepared for the first time to cover the phytochemical constituents and various pharmacological and therapeutic impacts of A. visnaga (L.) Lam., aiming to enrich Moroccan traditional knowledge.  Manuscript profile

  • Article

    2 - Simultaneous optimization of extraction of bioactive compounds and antioxidant activity of Ammi visnaga (L.) Lam aerial parts using response surface methodology
    Trends in Phytochemical Research , Issue 1 , Year , Spring 2024
    In this report, different extracts from the aerial parts of Ammi visnaga (L.), e.g., flowers, leaves, and stems were prepared using water, methanol, and ethanol. To optimize the extraction process, the design of mixtures was carried out using different extracting solven More
    In this report, different extracts from the aerial parts of Ammi visnaga (L.), e.g., flowers, leaves, and stems were prepared using water, methanol, and ethanol. To optimize the extraction process, the design of mixtures was carried out using different extracting solvents and their combinations. The special cubic model explained the variance of the TPC and the antioxidant activity of the extracts at a level of R2 > 95%. In general, the analysis of the model-derived response surfaces revealed that in binary mixtures (50% ethanol + 50% methanol), the yielded values of phenolic compounds and the antioxidant activity increase with the water proportion of different prepared mixtures. The ability of the quaternary mixture to extract the phenolic compounds was also positively and significantly influenced by the water content, creating a mild polar medium for the extraction of phenolic compounds. The phenolic profile of different extracts under study revealed the presence of a cocktail of active ingredients, including chlorogenic acid, caffeic acid, rutin, p-coumaric acid, etc. especially the flower extract of A. visnaga (L.). Manuscript profile