City and climate are two human made and natural systems that influence each other. The city that influences greenhouse gas emissions leads to global warming as a result of climate change. The main purpose of this study is to evaluate the impact of urban development on the climate change (a case study of Mashhad metropolis). The research method in this study is descriptive and analytical, in which by referring to library studies and field-based studies a theoretical framework is obtained; also, by determining evaluation options according to the negative effects and consequences of urban growth and development of Mashhad metropolis in recent decades on social systems, physical, functional, transportation and access are examined. In this study, the Iranian Leopold matrix method and rapid impact assessment matrix (RIAM) as well as Microsoft Excel, Arc GIS and Google Earth software have been used. Findings in this study indicate that the functional system with the range of letters -E and number -5 has the most destructive effects on climate change in this metropolis and the physical system with letters -B and number -2 has the least effects on the process. With the increase in population in the metropolis of Mashhad, urban growth and development is extended to villages and agricultural lands, and as a result, the change of use from agriculture to urban use occurs, leading to more greenhouse gas emissions and the creation of urban heat islands. So, in order to control such things, appropriate solutions in the system should be presented. Manuscript profile