Introduction:Diabetes is a chronic, metabolic disease characterized by elevated levels of blood glucose (or blood sugar), which leads over time to serious damage to the heart, blood vessels, eyes, kidneys and nerves. The aim of study was to determine the effect of endurance, resistance and combined trainings on glycemic control and lipid profile in type 2 diabetic patients. Material & Methods: Subjects selected between diabetic clinic patients of Valliasr hospital of Fasa and members of Fasa diabetic association. 40 patients with necessary conditions (medical history) are selected by physician and randomly divided to equal 4 groups: endurance, resistance, combined and control. Patients both received own medications (consuming pills & diet) and did trainings program in 8 weeks (3 sections per week) under trainer consideration. Plasma levels of total cholesterol (TC), triglycerides (TG), LDL, HDL, glycated hemoglobin (HbA1c),insulin, fasting blood sugar (FBS) and insulin resistance were measured before and after the intervention. Results: The results indicated that insulin concentration and HbA1c decreases and HDL increases after resistance training (p <0.05). Combined trainings reduced insulin and TC concentration and increased HDL level in compare to the control group (p <0.05). Any changes in lipid profile and glycemic control were observed after the endurance training. Conclusion: Our findings suggested that resistance and combined training improve insulin concentration and lipid profiles rather than endurance training in type 2 diabetic patients. Manuscript profile