Imbalance in the production of oxidative molecules and antioxidant activity plays an important role in carcinogenesis. This study was performed to evaluate the serum level of malondialdehyde (MDA) as oxidative damage marker, superoxide dismutase (SOD) as well as glutathione peroxidase (GPx) as an antioxidant defense system in non-Hodgkin's lymphoma (NHL). Twenty-five NHL patients and twenty-five healthy individuals were included in the study. The data showed that lower activity of enzymatic antioxidants (GPx, SOD) and higher MDA levels in NHL patients than in the control group. The results suggest that increased serum MDA and decreased SOD and GPx activity may be due to oxidative stress, which may play an important role in NHL formation. the role of oxidative stress in the pathogenesis of the NHL has not been extensively studied. Therefore, the present study aimed to measure the level of MDA as well as GPx and SOD activity in blood tissue collected from NHL patients compared with the control group. Manuscript profile

Breast cancer is one of the most common malignancies in women with the highest mortality rate in women. Oxidative stress characteristics play a large role in the risk factor of tumors. In this study, we measure the oxidative stress indices of malondialdehyde(MDA), Total antioxidant capacity(TAC) in women with breast cancer compared to healthy subjects.This case-control study was performed on 30 women with a definitive diagnosis of breast cancer and 30 healthy women. The subjects were matched in terms of age and sex and then blood samples were taken from them and collected in vials EDTA .Oxidative stress was measured by spectrophotometry. MDA level was significantly higher in cases (2.48± 0.73 ) compared to controls (1.4± 0.63 (. In contrast, there were lower TAC levels in cases compared to controls and was statistically significant . The data showed that higher MDA levels in BC patients than in the control group. The results suggest that increased serum MDA and decreased TCA activity may be due to oxidative stress, which may play an important role in BC formation. Manuscript profile

The role of oxidative stress is one of the most important factors in the development of cancer. In this study, the catalase activity and total antioxidant capacity in NHL patients were measures and compared with those in healthy subjects. The population of this study consisted of 25 patients with non-Hodgkin's lymphoma, diagnosed based on pathological findings. Total antioxidant capacity (TAC) and catalase catalytic activity (CAT) were determined by spectrophotometry. Based on the results, the CAT activity was significantly lower and TAC was lower (0.29±0.04 vs. 2.69±0.15; P-value=0.01) in NHL patients than in healthy subjects. The findings showed that these markers could be used as a prognosis in non-Hodgkin's lymphoma that oxidative stress may also be related to the NHL or increase the risk of disease. Manuscript profile

Zinc is one of the main and essential elements in pregnancy that its deficiency in this period causes disorders of the maternal and fetal immune system and disorders of the metabolic systems in pregnant women, and its deficiency is often observed in pregnant women. In this study, the effect on pregnant women with gestational diabetes (GDM) compared to pregnant women without gestational diabetes (NGT) will be discussed. Methods: In this study, fresh blood samples were taken from 50 pregnant women with gestational diabetes and 50 pregnant women without gestational diabetes. Blood samples were taken from both groups in the third trimester of pregnancy and then the obtained values were analyzed by Flame Atomic Absorption Spectrophotometry for Plasma zinc level (FAAS). Zinc levels in pregnant women with gestational diabetes were higher in comparison with pregnant women with non-gestational diabetes (93.4±77.57µmol/dl vs 66.35±53.74 µmol/dl). Conclusion: This study showed No significant differences between GDM and NGTwomen in the serum zinc levels. Manuscript profile