One of the most common and most dangerous diseases of blood fats are such as heart disease, diabetes and stroke, heart and brain. It can control the timely diagnosis, treatment and then prevention of complications is become very effective even without using medicine. Heart disease and diabetes file if patients has useful information that can be used to estimate blood fat timely diagnosis. In this paper we introduce a method based on data mining according to the information of patients' medical records to predict and detect blood lipid cardiovascular. And to identify patients with high blood lipids,we use a category based on neural network without feedback and pso algorithm to train the neural network to determine the appropriate value to reduce error the weights of the neural network . Simulation is done in MATLAB environment by using Body Fat data set, it shows the accuracy of 93.22 percent compared to the same methods, which means high accurate, higher detection sensitivity and Democrats. Manuscript profile