Ethnobotany, chemical composition and antibacterial activity of the essential oil from Achillea micranta L. in Golestan province
Subject Areas : Geneticmasome Mazandarani 1 , m,b Rezaei 2 , E.O Ghaemi, 3 , ب Behmanesh 4 , ع Ahmadi 5 , ا Chamani, 6
1 - Department of biology, Islamic Azad University-Gorgan branch, Gorgan, Iran
2 - Forests and Rangeland Institute, Tehran, Iran
3 - Department of biology, Golestan University of medical Sciences, Gorgan, Iran
4 - Rangeland department Gorgan Uuniversity, Gorgan, Iran
5 - Department of biology, Golestan University of medical Sciences, Gorgan, Iran
6 - . Rangeland department Gorgan Uuniversity, Gorgan, Iran
Keywords: Antibacterial activity, Essential oil, Ethnobotany, Achillea micranta L,
Abstract :
Achillea micranta L. is a wild endemic medicine herb with important therapeutic effects has been used in traditional north of Iran. GC-MS analysis of the isolated essential oil from flowering aerial parts of A. micranta resulted to identification of 23 constituents, that eucalyptol (1,8-cineol) with 19.9%, borneol (11.9%), camphor(11.1%) and thujene (5.1%) were the major constituent of essential oil studied, respectively. The antibacterial activity was individually evaluated against 2 tested bacteria. We concluded that the essential oil showed a good antibacterial activity against tested bacteria but the Gram-positive bacteria staphylococcus aureus was more sensitive. This study confirms that the essential oil of A. micranta L. possesses antibacterial properties in vitro. 1,8-cineol, borneol and camphor can be considered as the main antibacterial constituents of the oil studied.
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Benzic, N., Skocibusic, M., Dunkic, V., Radonic. A., (2003) Composition and antimicrobial activity of A.clavennae L. J.Essential, Phytother Res, 17(9): 1037-40.
Blumenthal, M., Busse, W.R., Goldberg, A, Grueuwald, J., Hall, T., (2000) In herbal medicine expanden commission E, 11, 282-285
Caralcantis, A.M., Baggio, C.H., Freitas, C.S., Reik, L., (2006) Safety and antinuclear efficacy studies of A. millefolium L. after chronic treatment in Wistar ratsg. Ethnopharm, 107,277-284
Fillippi, J, Lanfranchi, D.A., Prado, S., Baldovini, N., Melerhenrich, U.J. (2006) Composition, ethnobotanical and antibacterial of A.ligustica. Agric Food Chem, 54(17):6308-13.
Mockute, D., Judzeatieni, A., (2002) Chemical composition of the essential oils of Achillea millefolium L.Ssp.millefolium growing wild in Vilnuse. F.J. 13, 97-102.
Rustaiyan, A., Komeilizadeh, H.M.S., Shariatpanahi, Jassbi, A., Masoudi., S., (1998) Comparative study of the essential oils of three Achillea species from Iran. J. Essential Oil Res.10, pp.207-209.
Senatore, F., Napolianto, F., Arnold, A.N., Bruno, M., Herz, W., (2003) Composition and antimicrobial activity of the essential oil of Achillea falcata L. Flavour and Fragrance Journal.20, 3, 291-294.
Simic, N., Andjelkonvic, S., Palic, R., (2000) Composition and antibacterial activity of A. chrisochoma essential oil , Journal of essential oil, Res 12, pp. 784- 787.
Suleimenov, Y.M., Atazhanova, G.A., Ozek, T., Demirci, B., Kulijasov, A.T., Adekenov, S.M. and Baser, K.H.C., (2004) Essential oil composition of three species of Achillea from Kazakhestan. Chemistery natural compounds , 37, 447-450.
Van Wyk, B., Gericke, N., (2000) People's plants. Pretoria: Briza Publications, pp. 128.
Konyaliogla, S., karamenderes, C., (2005) The protective effects of Achilla L.species native in Turkey against H2O2-induced oxidative damage in human erythrocytes and leucocytes .g.of Ethnopharma 102-221-227.
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Angihotri, V.K., Lattoo, S.K., Thappa, R.K. Kaul, P., Oazi, G.N., (2005) Chemical variability in the essential oil components of Achillea millefolium agg in India. Plantamed, 71(3): 280-3.
Baser, K.H., Demirci, B., Kocak, S., Akinci, C., Malyer, H., Gulerus, G., (2002) Composition and antimicrobial activity essential oils of A. multifida. Planta Med. 10: 941-3.
Benzic, N., Skocibusic, M., Dunkic, V., Radonic. A., (2003) Composition and antimicrobial activity of A.clavennae L. J.Essential, Phytother Res, 17(9): 1037-40.
Blumenthal, M., Busse, W.R., Goldberg, A, Grueuwald, J., Hall, T., (2000) In herbal medicine expanden commission E, 11, 282-285
Caralcantis, A.M., Baggio, C.H., Freitas, C.S., Reik, L., (2006) Safety and antinuclear efficacy studies of A. millefolium L. after chronic treatment in Wistar ratsg. Ethnopharm, 107,277-284
Fillippi, J, Lanfranchi, D.A., Prado, S., Baldovini, N., Melerhenrich, U.J. (2006) Composition, ethnobotanical and antibacterial of A.ligustica. Agric Food Chem, 54(17):6308-13.
Mockute, D., Judzeatieni, A., (2002) Chemical composition of the essential oils of Achillea millefolium L.Ssp.millefolium growing wild in Vilnuse. F.J. 13, 97-102.
Rustaiyan, A., Komeilizadeh, H.M.S., Shariatpanahi, Jassbi, A., Masoudi., S., (1998) Comparative study of the essential oils of three Achillea species from Iran. J. Essential Oil Res.10, pp.207-209.
Senatore, F., Napolianto, F., Arnold, A.N., Bruno, M., Herz, W., (2003) Composition and antimicrobial activity of the essential oil of Achillea falcata L. Flavour and Fragrance Journal.20, 3, 291-294.
Simic, N., Andjelkonvic, S., Palic, R., (2000) Composition and antibacterial activity of A. chrisochoma essential oil , Journal of essential oil, Res 12, pp. 784- 787.
Suleimenov, Y.M., Atazhanova, G.A., Ozek, T., Demirci, B., Kulijasov, A.T., Adekenov, S.M. and Baser, K.H.C., (2004) Essential oil composition of three species of Achillea from Kazakhestan. Chemistery natural compounds , 37, 447-450.
Van Wyk, B., Gericke, N., (2000) People's plants. Pretoria: Briza Publications, pp. 128.
Konyaliogla, S., karamenderes, C., (2005) The protective effects of Achilla L.species native in Turkey against H2O2-induced oxidative damage in human erythrocytes and leucocytes .g.of Ethnopharma 102-221-227.