The status of oxidative stress and some trace elements, hematological and serum biochemical indices in dairy cows with left displacement of the abomasum
Subject Areas :
Veterinary Clinical Pathology
Kambiz Kiani Monfared
1
(
Graduate of DVM, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran
)
Gholam Reza Mohammadi
2
(
Professor, Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
)
Seyed alireza Taghavi razavizadeh
3
(
Asistant professor, Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
)
Mohammad Heidarpour
4
(
Associate professor, Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
)
Received: 2018-05-03
Accepted : 2018-12-05
Published : 2018-12-22
Keywords:
dairy cows,
trace elements,
Oxidative stress,
LDA,
Abstract :
Left displacement of the abomasum (LDA) is one of the most important production disorders. In order to compare the status of some hematological and serum biochemical indices, trace elements and oxidative stress of cows with and without LDA, blood samples were taken from 30 dairy cows with LDA and 30 healthy cows in early lactation period. Haematological parameters, total protein, fibrinogen, Ca, Mg, bilirubin, uric acid, albumin, cholesterol, triglyceride, urea, creatinine and AST (Aspartate aminotransferase), ALP (Alkaline phosphatase), GGT (Gamma- glutamyl transferase), CPK (Creatine phosphokinase) enzymes, Fe, Zn, Cu, Se, MDA and total antioxidant status were measured. Although the results showed significant differences in PCV, RBC, MCHC, lymphocyte, monocyte, fibrinogen, bilirubin, albumin, cholesterol, calcium, uric acid, AST and ALP enzymes between the two groups (p<0.05), but the occurrence of oxidative stress and changes in the levels of trace elements were not significant between the LDA affected and healthy cows. In LDA affected cattle, significant increase of PCV might be due to dehydration while increasing of monocyte and decreasing of lymphocyte counts could also be due to stressful condition or probable infections in early lactation. Anorexia, food deprivation and withdrawal of calcium from milk in early lactation may play a role in decreasing of albumin, cholesterol and calcium. Liver lipidosis and fasting along with biliary duct obstruction may be effective on increasing AST activity and bilirubin respectively in cows with LDA. It seems that early diagnosis and treatment of LDA can prevent the occurrence of sever changes in oxidative stress status and homeostasis of cow’s body.
References:
Abd El-Raof, Y.M. and Ghanem, M.M. (2007). Clinical, hematobiochemical and ultrasonograohic study in abomasal displacement in cows with trials of treatment. Proceeding of the Second Scientific Conference, Faculty of Veterinary Medicine, Benha University, pp: 290-307.
Benzie, I.F.F. and Strain, J.J. (1996).The ferric reducing ability of plasma (FRAP) as a measure of antioxidant power: The FRAP Assay. Analytical Biochemistry, 239(1): 70-76.
Cao, G. and Prior, R. (1998). Comparison of different analytical methods for assessing total antioxidant capacity of human serum. Clinical Chemistry, 44(6): 1309-1315.
Ceil, P. (2011a). Biomarkers of oxidative stress in ruminant medicine. Immunopharmacology and Immunotoxicology, 33(2): 233-240.
Celi, P. (2011b). Oxidative stress in ruminants. In: Oxidative stress in applied basic research and clinical practice, Armstrong, D. editor in chief, USA: Humana Press, pp: 191-231.
Chapple, I.Lc. (1997). Reactive oxygen species and antioxidants in inflammatory disease. Journal of Clinical Periodontology, 24(5): 287-96.
Dezfouli, M., Eftekhari, Z., Sadeghian, S., Bahounar, A. and Jeloudari, M. (2013). Evaluation of hematological and biochemical profiles in dairy cows with left displacement of the abomasum. Comparative Clinical Pathology, 22(2): 175-179.
Diaz de Barboza, G., Guizzardi, S., Moine, L. and Tolosa de Talamoni, N. (2017). Oxidative stress, antioxidants and intestinal calcium absorption. World Journal of Gastroenteroly, 23(16): 2841-2853.
Fürll, M., Dabbagh, M.N., Kirbach, H., Nauruschat, C., Sattler, T. and Wilken, H. (2003). The antioxidative state before and after a diagnosed abomasal displacement in cows. Acta Veterinaria Scandinavica, 44(Suppl): 37-42.
Halliwell, B. (2012). Free radicals and antioxidants: updating a personal view. NutritionReview, 70(5): 257-265.
Hassanpour, A., Saranjam, N. and Amoghli Tabrizi, B. (2011). Antioxidant concentration status in the serum of cows with left displacement abomasum. Global Veterinaria, 7(5): 478-481.
Karimi, N., Mohri, M., Seifi, H.A., Azizzadeh, M. and Heidarpour, M. (2015). Relationship between trace elements, oxidative stress subclinical ketosis during transition period dairy cows. Iranian Journal of Veterinary Science and Technology, 7(2): 46-56.
Maden, M., Ozturk, A.S., Bulbul, A., Avci, G.E. and Yazar, E. (2012). Acute-phase proteins, oxidative stress, and enzyme activities of blood serum and peritoneal fluid in cattle with abomasal displacement. Journal of Veterinary Internal Medicine, 26(6): 1470-1475.
Patelli, T.H.C., Souza, F.A.A., Rosa, F., Barreiros, T.R.R. and Marques, L.C. (2013). Economic impact of displaced abomasum on a dairy farm in Carambei, Parana. ARS Veterinaria, Jaboticabal, 29(1): 8-12.
Placer, Z., Cushman, L. and Johnson, B. (1966). Estimation of product of lipid peroxidation (malonyldialdehyde) in biochemical system. Analytical Biochemistry, 16: 359-364
Radostits, O.M., Gay, C.C., Hinchliff, K.W. and Constable, P.D. (2017). A Textbook of Disease of Cattle, Sheep, Pigs, Goats and Horses. 11th ed., UK: London, Saunders, pp: 502-514.
Sahinduran, S. and Koray Albay, M. (2006). Haematological and biochemical profiles in right displacement of abomasums in cattle. Revue de Médecine Vétérinaire, 157(7): 352-356.
Shaver, R.D. (2001). Prevention of displaced abomasums. Proceeding of Tri-state Dairy Nutrition Conference, April 17-18.
Stengärde, L., Holtenius, K., Tråvén, M., Hultgren, J., Niskanen, R. and Emanuelson, U. (2010). Blood profiles in dairy cows with displaced abomasums. Journal of Dairy Science, 93(10): 4691-4699.
Stockham, S.L. and Scott, M.A. (2008). Fundementals of Veterinary Clinical Pathology. 2nd ed., USA: Wiley Blackwel, pp: 70, 260-271, 411- 493.
Winden, S.V. and Kuiper, R. (2003). Left displacement of the abomasum in dairy cattle: Recent developments in epidemiological and etiological aspects. Veterinary Research, 34(1): 47-56.
Zadnik, T. (2003). A comparative study of the hemato-biochemical parameters between clinically healthy cows and cows with displacement of the abomasum. Acta Veterinaria, 53(5-6): 297-309.
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Abd El-Raof, Y.M. and Ghanem, M.M. (2007). Clinical, hematobiochemical and ultrasonograohic study in abomasal displacement in cows with trials of treatment. Proceeding of the Second Scientific Conference, Faculty of Veterinary Medicine, Benha University, pp: 290-307.
Benzie, I.F.F. and Strain, J.J. (1996).The ferric reducing ability of plasma (FRAP) as a measure of antioxidant power: The FRAP Assay. Analytical Biochemistry, 239(1): 70-76.
Cao, G. and Prior, R. (1998). Comparison of different analytical methods for assessing total antioxidant capacity of human serum. Clinical Chemistry, 44(6): 1309-1315.
Ceil, P. (2011a). Biomarkers of oxidative stress in ruminant medicine. Immunopharmacology and Immunotoxicology, 33(2): 233-240.
Celi, P. (2011b). Oxidative stress in ruminants. In: Oxidative stress in applied basic research and clinical practice, Armstrong, D. editor in chief, USA: Humana Press, pp: 191-231.
Chapple, I.Lc. (1997). Reactive oxygen species and antioxidants in inflammatory disease. Journal of Clinical Periodontology, 24(5): 287-96.
Dezfouli, M., Eftekhari, Z., Sadeghian, S., Bahounar, A. and Jeloudari, M. (2013). Evaluation of hematological and biochemical profiles in dairy cows with left displacement of the abomasum. Comparative Clinical Pathology, 22(2): 175-179.
Diaz de Barboza, G., Guizzardi, S., Moine, L. and Tolosa de Talamoni, N. (2017). Oxidative stress, antioxidants and intestinal calcium absorption. World Journal of Gastroenteroly, 23(16): 2841-2853.
Fürll, M., Dabbagh, M.N., Kirbach, H., Nauruschat, C., Sattler, T. and Wilken, H. (2003). The antioxidative state before and after a diagnosed abomasal displacement in cows. Acta Veterinaria Scandinavica, 44(Suppl): 37-42.
Halliwell, B. (2012). Free radicals and antioxidants: updating a personal view. NutritionReview, 70(5): 257-265.
Hassanpour, A., Saranjam, N. and Amoghli Tabrizi, B. (2011). Antioxidant concentration status in the serum of cows with left displacement abomasum. Global Veterinaria, 7(5): 478-481.
Karimi, N., Mohri, M., Seifi, H.A., Azizzadeh, M. and Heidarpour, M. (2015). Relationship between trace elements, oxidative stress subclinical ketosis during transition period dairy cows. Iranian Journal of Veterinary Science and Technology, 7(2): 46-56.
Maden, M., Ozturk, A.S., Bulbul, A., Avci, G.E. and Yazar, E. (2012). Acute-phase proteins, oxidative stress, and enzyme activities of blood serum and peritoneal fluid in cattle with abomasal displacement. Journal of Veterinary Internal Medicine, 26(6): 1470-1475.
Patelli, T.H.C., Souza, F.A.A., Rosa, F., Barreiros, T.R.R. and Marques, L.C. (2013). Economic impact of displaced abomasum on a dairy farm in Carambei, Parana. ARS Veterinaria, Jaboticabal, 29(1): 8-12.
Placer, Z., Cushman, L. and Johnson, B. (1966). Estimation of product of lipid peroxidation (malonyldialdehyde) in biochemical system. Analytical Biochemistry, 16: 359-364
Radostits, O.M., Gay, C.C., Hinchliff, K.W. and Constable, P.D. (2017). A Textbook of Disease of Cattle, Sheep, Pigs, Goats and Horses. 11th ed., UK: London, Saunders, pp: 502-514.
Sahinduran, S. and Koray Albay, M. (2006). Haematological and biochemical profiles in right displacement of abomasums in cattle. Revue de Médecine Vétérinaire, 157(7): 352-356.
Shaver, R.D. (2001). Prevention of displaced abomasums. Proceeding of Tri-state Dairy Nutrition Conference, April 17-18.
Stengärde, L., Holtenius, K., Tråvén, M., Hultgren, J., Niskanen, R. and Emanuelson, U. (2010). Blood profiles in dairy cows with displaced abomasums. Journal of Dairy Science, 93(10): 4691-4699.
Stockham, S.L. and Scott, M.A. (2008). Fundementals of Veterinary Clinical Pathology. 2nd ed., USA: Wiley Blackwel, pp: 70, 260-271, 411- 493.
Winden, S.V. and Kuiper, R. (2003). Left displacement of the abomasum in dairy cattle: Recent developments in epidemiological and etiological aspects. Veterinary Research, 34(1): 47-56.
Zadnik, T. (2003). A comparative study of the hemato-biochemical parameters between clinically healthy cows and cows with displacement of the abomasum. Acta Veterinaria, 53(5-6): 297-309.
