Association of ACTN3 Gene Polymorphism Strength performance of Adolescent wrestlers in Ardabil
Subject Areas : Physical Activity and Health
1 - Department of Physical Education, Mahabad Branch, Islamic Azad University, Mahabad, Iran
Keywords: Genetics, ACTN3, Wrestlers, polymorphism, Power Performance,
Abstract :
Objective: Both "environment" and "genetics" are considered as essential factors for the athletic performance of elite people. The aim of this study was to investigate the relationship between ACTN3 gene polymorphism and strength performance in novice junior wrestlers in Ardabil.Methods: The statistical sample of this study was 15 beginner juvenile wrestlers in Ardabil in the age range of 11-16 years. Subjects had a history of 6 months to 1 year. Measured athletic performance included upper body strength (pre-chest test) and lower body strength (Scott test). ACTN3 gene polymorphism was determined and compared using salivary samples using polymerase chain reaction and direct DNA sequencing (Tetra-ARMs PCR). After examining the normality and homogeneity of the data, independent group t-test and chi-square test were used for analysis. Results: The results of the present study showed that a significant difference was observed in the frequency of ACTN3 gene polymorphism in beginner juvenile wrestlers. The frequency of polymorphisms was higher in healthy homozygous (RR) and heterozygous (RX) genotypes, respectively (n = 12 (RR) and n = n (RX), P = 0.001). The results of t-test analysis of independent groups showed a significant discrepancy between upper and lower body strength performance indices between polymorphisms (RR, RX) (upper body: P = 0.3, lower body strength: P = 0.4).Conclusion: In the present study, the results showed the superiority of healthy homozygous (RR) genotype in ACTN3 gene of novice male adolescent wrestlers in Ardabil, and despite the significant difference in strength performance indices between the two genotypes (RR and RX); However, due to the high strength performance in the RR genotype compared to the RX, it can be said that this genotype can be considered as an important factor in talent identification in juvenile wrestlers, especially in mountainous areas.
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