Effect of secondary metabolite compounds of Dracocephalum kotschyi Boiss plant on synthesis of Cu nanoparticles

Subject Areas : Natural Products: Isolation and Characterization

Malihe Samadi Kazemi ¹ , Zohre Imani ²

1 - Department of Chemistry, Faculty of Science, Bojnourd Branch, Islamic Azad University, Bojnourd 9417697796, Iran
2 - Department of Chemistry, Faculty of Science, Bojnourd Branch, Islamic Azad University, Bojnourd 9417697796, Iran

Received: 2023-06-18 Accepted : 2023-11-17 Published : 2023-12-07

Keywords: Secondary metabolites, CuNPs, Dracocephalum kotschyi Boiss, Extract, Essential oil, Antibacterial,

Abstract :

Medicinal plants are a rich source of secondary metabolite. In the present research, the dried aerial parts of Dracocephalum kotschyi Boiss were extracted by digestion method. Copper nanoparticles were synthesized from the combination of the extract with copper chloride solution at a ratio of 1:4. The characteristics of copper nanoparticles by ultraviolet-visible spectrometry (UV-Vis), X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X- ray spectroscopy (EDS), Brunauer-Emmett-Teller (BET) and fourier transform infrared spectroscopy (FT-IR) were analyzed. The SEM analysis predicted the size of copper nanoparticles to be 63.28 nm. The EDS spectrum confirmed the presence of copper nanoparticles. BET analysis predicted mesoporous structure of copper nanoparticles. Thirty-three (31) compounds in the essential oil of plant identified, which constituted 99.7% of the essential oil and 8 major compounds were perillaacetate (49.0 %), 2-methyl-1-octen-3-yne (17.2%), D-limonene (15.0%), 1,8-cineole (5.2%), trans-alpha-ocimene (2.4%), p-mentha-1(7),8(10)-dien-9-ol (1.1%), sabinene (1.4%) and 4-terpineol (1.5%).

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