Antifungal effect of ganoderma mushroom extract on Candida albicans isolated from pulmonary specimen
Subject Areas : microbiologysanaz rostami nejad 1 , Mohammad Dakhili 2 , Seyed Ali Rezaei 3
1 - Microbiologiy،basic sciences،azad eslami،qom،iran
2 - Department of Laboratory Sciences, Faculty of Medicine, Qom Islamic Azad University, Qom, Iran
3 - Department of Microbiology, Basic Sciences, Qom Islamic Azad University, Qom, Iran.
Keywords: antifungal effect, Candida albicans, Ganoderma mushroom extract, Pulmonary infection,
Abstract :
Introduction & Objective: Candida infection is caused by overgrowth of Candida species, especially albicans, in immunocompromised individuals. This infection may be resistant to the treatment and sometimes become chronic, as well as sometimes the patients will return to the infection after treatment. Pulmonary aspergillosis is also one of the most important causes of fungal infections in humans and animals and leads to pulmonary infection in immunocompromised individuals. With increasing drug resistance, an attempt to provide antifungal or antimicrobial drugs is needed. The increasing use of medicinal plants in medical treatment, this branch of complementary medicine, has a special place in the treatment of diseases. The aim of this study was to compare the effect of Ganodermalocydom fungus extract on the growth of Candida albicans isolated from pulmonary infections in laboratory conditions and compare them with the standard strain. Materials and Methods: In this experimental study, the antifungal effects of the extract on Candida albicans were evaluated based on CLSI standards. Results: The extract had a good effect on Candida albicans inhibition.. Conclusion: Ganoderma fungus extract showed antifungal effects on Candida albicans.
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