Study of potential Ricinus communis in Absorption of Metformin Hydrochloride

Subject Areas : environmental management

Sepideh  Hosseini ¹ (MSc. of Environmental Management, Science and Research Branch, Islamic Azad University, Tehran, Iran)
Roxana  Moogouei ² (Assistant Professor, Departmant of Environmental planning, Management and Education, Islamic Azad University, Tehran, North Branch. *(Corresponding Author).)
Mehdi  Borghei ³ (3-Professor , Department of Chemistry Engineering, Sharif University of Technology, Tehran, Iran.)
Golnaz  Tjadod ⁴ (Assistant Professor, Department of Biology, North Tehran Branch, Islamic Azad University, Tehran, Iran.)

Received: 2015-06-09 Accepted : 2015-08-22 Published : 2017-06-22

Keywords: Ricinus communis”, Phytoremediation, Metformin Hydrochloride,

Abstract :

Background and Objective: This study has considered for potential plant species Ricinus communis of remediation metformin hydrochloride drug. Method: In phytoremediation method for remediation of metformin hydrochloride solution, the first Ricinus communis has been cultured in the soil and then metformin absorption of solution has been kept with 20 ppm and 50 ppm in control and laboratory situation, for 14 days. Finally the solution has been injected to HPLC device to detected of remind metformin hydrochloride drug. Findings: the end of 14 days has been recognized Ricinus communis has %45.06 and 21 % efficiency in two different 20 ppm and 50 ppm. Discussion and Conclusion: This study has been shown that the maximum %45.06 has been remediated from metformin hydrochloride solution that related to minimum (20 ppm) of metformin solution. The result has been shown that Ricinus communis can be middle species for remediation of metformin hydrochloride drug from metformin hydrochloride solution.

References:

1. , D., Smith, R.D., Raskin, I., Phytoremediation. Ann. Rev. plant Physio. Mol. Biol. 1998; 49: 643-648.


2. Chakraborty D., Maji S., Bandyopadhyay A., Basu S.,Biosorption of Cesium-137 and strontium-90by mucilaginous seeds of Ocimum basilicum, Bioresource Technology 2007; 98, 2949-2952.


3. Nikolaou A, Meric S, fatta D. Occurrunce patterns of pharmaceuticals in water and wastewater environments. Anal Bional Chem 2007; 387: 1225-1234.


4. Carlsson C, Johansson A-K, Alvan G, Bergman K, Kühler T. Are pharmaceuticals potent environmental pollutants?: part I: environmental risk assessments of selected active pharmaceutical ingredients. Sci Total Environ 2006; 364:67–87.


5. Fent K, Weston AA, Caminada D. Ecotoxicology of human pharmaceuticals. Aquat Toxicol 2006; 76:122–59.


6. Zuccato E, Castiglioni S, Fanelli R, Reitano G, Bagnati R, Chiabrando C, et al. Pharmaceuticals in the environment in Italy: causes, occurrence, effects and control. Environ. Sci. Pollut. Res 2006; 13:15–21.


7. Pilon-Smits EAH, Freeman JL.Environmental cleanup using plants: Biotechnological advances & ecological consideration. Front Ecol Environ 2006;4:203-210.


8. Huges, J. B., Shanks, J.,Vanderford, M., Lauritzen,J.,& Bhadra, R.Transformation of TNT by aquatic plants & plant tissue cultures. Environmental science & technology 1997;31: 266-271.


9. Salt, D. E., Smith , R. D., Raskin, I. Phytoremediation. Annu. Rev. plant physiol. Plant Mol Biol 1998; 49: 643-668.


10. Scheurer M, Sacher F, Brauch H-J. Occurrence of the antidiabetic drug metformin in sewage and surface waters in Germany. Jornal of Environmental Monitoring 2009; 11: 1608-1613.


11. قهرمان. احمد، 1367، فلور ایران، موسسه تحقیقات جنگل ها و مراتع. جلد 19، صفحه 2348.


12. کرباسی. ع، منوری. س.م و موگویی. ر،1387، مدیریت زیست محیطی آب زی پروری در منطقه سراب گردو، فصل نامه علوم و تکنولوژی محیط زیست، 10 (1)، صص 159-169.


13. Brown.D.S¸ constructed wetland in the U.S.A water Quality Omprovement¸1994; 4: 24-28.


14. مصطفایی. عبدالله، بی تا ،روزنامه اعتماد، شماره 1977،صفحه7.


15. Choudhary AK, Kumar S, Sharma C. Constructed wetlands: an option for pulp and paper mill wastewater treatment. Electron J Environ Agric Food Chem; 2011, 10:3023–37.


16. Yoon Y., Cao X., Qixing Zhou Q., Ma L.Q., Accumulation of Pb, Cu and Zn in native plants growing on a contaminated Florida site, Science of the Total Environment 2006; 368: 456–464.


17. برقعی.م،  ارجمندی. ر و موگویی. ر، بی تا، بررسی توان Chenopodium album در جذب و تجمع پایدار سزیم، 15(3)، صص 1-11.


18. Eggen, T., Normann, T., Grave, K., Hormazabal, V. Uptake and translocation of metformin, ciprofloxacin and narasin in forage and crop plants. Chemosphere 2011., 885: 26-33.


19. دریا بیگی زند. ع، بیدهندی. غ، مهردادی. ن و شیردم. ر، 1389، توانایی گونه های گیاهی مختلف در حذف ترکیبات نفتی از خاک و تاثیر آلودگی نفتی بر رشد این گونه های گیاهی، فصل نامه علوم و تکنولوژی محیط زیست، 12 (4)، صص 41-57.


20. Cui, H., Hense, B.A., Muller, J., Schrödera, P. Short term uptake and transport process for metformin in roots of Phragmites australis and Typha latifolia.Chemosphere 2015.,134:307-312.