A brief review of the use of nanomaterials in the treatment of diabetic wounds
Subject Areas : Applications of NanostructuresRazieh Sanjari 1 , Mohsen Forozanfar 2 , Fatemeh Honarasa 3 , Mohammad Amin Edalatmanesh 4 , Heydar Aqababa 5
1 - Department of Biology, Shi C., Islamic Azad University, Shiraz, Iran.
2 - Department of Biology, Marv. C., Islamic Azad University, Marvdasht, Iran.
3 - Department of Chemistry, Shi. C., Islamic Azad University, Shiraz, Iran.
4 - Department of Biology, Shi C., Islamic Azad University, Shiraz, Iran.
5 - Department of Biology, Ars. C., Islamic Azad University, Arsanjan, Iran.
Keywords: Nanomaterials, Wound, Diabetes, Repair, Inflammation.,
Abstract :
Skin wounds and reducing their healing time are considered an important aspect of medicine. Wound healing, as a natural biological process, involves the interrelation of cellular processes in stage of researched and planned in terms of sequence and time intervals, and any defect in this process causes delayed wound healing. Diabetic ulcers are a common complication of diabetes, caused by impaired blood flow and immune function. Treatment of these wounds is challenging due to clinical complexities and the need for effective tissue repair. In recent years, nanomaterials have been introduced as a promising option in improving the treatment of diabetic wounds. Nanomaterials, with their unique characteristics, including high surface-to-volume ratio and specific physical and chemical properties, can serve as effective tools in wound healing. These materials include metal nanoparticles (such as silver and gold), carbon nanotubes, and polymer nanocomposites, each of which plays a specific role in the wound healing process. The mechanisms of action of nanomaterials include antiseptic properties, stimulation of tissue repair, and control of inflammation. Also, the use of nanomaterials in advanced dressings and targeted drug delivery systems can help accelerate the wound healing process. However, challenges such as toxicity and production cost must be considered. This study examines the clinical applications of nanomaterials in the treatment of diabetic wounds and to improve treatment outcomes.
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