The effect of 12 weeks of aquatic exercise on lipid profile and TSH hormone in women with polycystic ovary syndrome and hypothyroidism
Subject Areas : Sports Science and Healthy
Shabnam Talebi Kharzoughi
1
,
خسرو جلالی
2
,
Farzaneh Taghian
3
1 - Department of Physical Education and Sport Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
2 - Department of Physical Education and Sport Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
3 - Department of Physical Education and Sport Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
Keywords: polycystic ovary, TSH, exercise in water, lipid profile, Hypothyroidism,
Abstract :
Polycystic ovary syndrome is a common endocrine and metabolic disorder in women of reproductive age, affecting 15 to 20 percent of women. Polycystic ovary is the most important cause of infertility in women of reproductive age. The prevalence of polycystic ovary varies in different countries and is on average 5 to 10%, but in some areas it reaches 26% The cause of polycystic ovary may be a range of endocrine disorders such as hypothalamus-pituitary-adrenal axis disorders, ovarian disorders and insulin signaling Polycystic ovaries increase the production of androgens from the ovaries. Despite the known phenotypes for this syndrome, the pathogenesis of this syndrome is still unclear This syndrome is a multifactorial disorder including genetics, epigenetics and environmental variables, as well as factors and immune disordersIn addition, lifestyle factors affect the course and pathogenesis of polycystic ovary syndrome. Despite the progress achieved in the treatment and management of this disease, little is known about the molecular mechanism and pathogenic signaling pathways of this disease. Recent research has shown that several factors including age, environment and lifestyle and disease status can change the clinical manifestations of polycystic ovary. Exercise increases the activity of the hypothalamic-pituitary-adrenal axis and subsequently reduces androgens. Glucocorticoids that are secreted during exercise prevent the release of LH hormone from the pituitary gland and estrogen and progesterone from the ovary. Based on the results of researches, moderate intensity exercise reduces the secretion of LH hormone. Aerobic exercise is beneficial in reducing circulating testosterone levels. However, paradoxically, it is the effect of strength training that seems to increase the level of androgens. However, four months of strengthening training in women with polycystic ovaries has caused a decrease in testosterone levels. The latest international clinical guidelines have suggested lifestyle interventions and exercise training as the first line of treatment for infertility caused by anovulation in women with polycystic ovariesThyroid disorders are commonly seen in patients with polycystic ovaries. Other articles reported that about 12 to 25% of the populations of polycystic ovary patients have subclinical hypothyroidism .Patients with subclinical hypothyroidism face an increased risk of metabolic diseases such as obesity, insulin resistance, and hyperlipidemia, similar to patients with polycystic ovaries. However, there are few evidences that have examined these two metabolic diseases at the same time. Considering the overlap of the symptoms of these two diseases, the occurrence of these two together will definitely have an effect on the treatment and control of symptoms. Given the relationship between polycystic ovary syndrome and hypothyroidism and the lack of investigation of hormonal indices in previous studies, A prescribed exercise regimen for the treatment of polycystic ovary patients has not yet been formulated, this study was conducted to investigate the effect of aquatic exercise on the hormonal index TSH and lipid profile in patients with polycystic ovary syndrome and hypothyroidism. The present study is a semi-experimental pre-test-post-test with a control group. In this study, 30 patients with polycystic ovary syndrome and hypothyroidism were studied in two groups of 15. The variables and indicators under study were examined and analyzed at the beginning of the study and after 12 weeks in the studied individuals. The study group underwent regular water exercises according to the protocol during these 12 weeks. The data were analyzed using SPSS software. The results of this study showed that physical exercises can effectively improve the lipid profile in patients. The mean BMI of patients was 22.63 in the control group and 22.79 in the case group. The mean TSH in the control group was 8.27 and in the case group was 7.69. The studies conducted on the TSH of the studied patients showed that after 12 weeks of training in water, the serum level of TSH decreases significantly. So the average TSH has dropped from 7.96 to 3.90 in the intervention group. It seems that aquatic exercise for 12 weeks can improve lipid profiles in patients with polycystic ovary syndrome and hypothyroidism. The present study, by examining TSH in patients with polycystic ovary syndrome and hypothyroidism, showed that regular aquatic exercise can effectively reduce TSH levels and thus reduce the need for thyroid medications. Given the results obtained in this regard, the dosage of medications received and changes in TSH levels in these patients should be considered by relevant specialists. Keywords: polycystic ovary, exercise in water, lipid profile
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